Jennings, D. H.
The Physiology of Fungal Nutrition
Cambridge University Press 2007.7
638 pp.(P)
ISBN 0-521-03816-2
12,700円
Contents
1. Primary active transport/ 2. The relationship between membrane transport and growth/ 3. Walls and membranes/ 4. The vacuolar compartment (vacuole)/ 5. Carbon/ 6. Nitrogen/ 7. Phosphorus/ 8. Sulphur/ 9. Growth factors/ 10. Potassium and other alkali metal cations/ 11. Multivalent metals (required or toxic)/ 12. Organic acids/ 13. Water relations and salinity/ 14. Nutrient movement within the colony/ Literature cited/ Index/
* The nutrition of a vegetative fungal colony can be viewed as a web of interconnected processes. In this volume, the author provides a mechanistic basis to the subject, focusing on processes at the plasma membrane, considering the modulating effects of the fungal wall and describing the fate of nutrients entering the fungus.
* The major emphasis is physiological, but biomechanical and molecular biological information has been drawn upon as appropriate to reflect the power of the multifaceted approach and encourage such further study. A comprehensive review of what is known for the more commonly studied fungal species is complemented by information on other fungi to provide an indication of the diversity of nutritional processes that exist in the fungal kingdom. *
Amsler, C. D. ed.
Algal Chemical Ecology
Springer-Verlag 2008.1
314 pp.(H)
ISBN 3-540-74180-1
25,400円
Contents
Part.1: The Chemistry of Algal Secondary Metabolism: 1.1 Introduction/ 1.2 Conceptual Framework/ 1.3 Compound Classes/ 1.4 Algal Chemistry/ 1.5 Summary/ References/ Part.2: Macroalgal Chemical Defenses and Their Roles in Structuring Tropical Marine Communities: 2.1 Introduction/ 2.2 The Tropical Marine Environment/ 2.3 Tropical Macroalgal Natural Products/ 2.4 Tropical Chemically Defended Macroalgae/ 2.5 Tropical Macroalgal Chemical Defenses and Community Structure/ 2.6 Conclusions/ References/ Part.3: Macroalgal Chemical Defenses and Their Roles in Structuring Temperate Marine Communities: 3.1 Interactions in Diverse Macroalgal Communities/ 3.2 Defense Strategies/ 3.3 Consequences of Algal Defenses to Grazers/ 3.4 Allelopathy in Space Competition and in Resisting Epibiotism/ 3.5 Case Study of F. vesiculosus in the Eutrophic Northern Baltic Sea: Genotypically Variable, Plastic Phlorotannins as Chemical Defenses/ 3.6 Conclusions/ References/ Part.4: Macroalgal Chemical Defenses in Polar Marine Communities: 4.1 Introduction/ 4.2 Western Antarctic Peninsula/ 4.3 McMurdo Sound, Antarctica/ 4.4 The Arctic/ References/ Part.5: Macroalgal and Cyanobacterial Chemical Defenses in Freshwater Communities: 5.1 Introduction/ 5.2 Cyanobacteria and Macroalgae: Evolutionary and Ecological Perspectives/ 5.3 Cyanotoxin Structure and Synthesis/ 5.4 Macroalgal Secondary Metabolites/ 5.5 Inducible Synthesis of Secondary Metabolites/ 5.6 Effects on Consumers/ 5.7 Allelopathic Effects/ 5.8 Secondary Metabolites and Trophic Interactions/ 5.9 Bioaccumulation of Metabolites at Higher Trophic Levels/ 5.10 Summary/ References/ Part.6: New Perspectives for Addressing Patterns of Secondary Metabolites in Marine Macroalgae: 6.1 Interpreting Patterns of Chemical Defense in the Marine Environment/ 6.2 A Brief Review of Macroscale Patterns of Algal Chemical Defenses/ 6.3 Patterns of Secondary Metabolites at the Microscale/ 6.4 Advances in the Characterization of Patterns of Chemical Defenses/ 6.5 Conclusion/ References/ Part.7: Macroalgal Models in Testing and Extending Defense Theories: 7.1 Introduction/ 7.2 Defense Theories/ 7.3 The Status of Defense Models in Terrestrial Plant Ecology/ 7.4 Empirical Tests of Defense Theories in Marine Studies/ 7.5 Summary and Conclusions/ References/ Part.8 Ecological and Physiological Roles of Dimethylsulfoniopropionate and its Products in Marine Macroalgae: 8.1 Introduction/ 8.2 Dimethylsulfoniopropionate/ 8.3 The DMSP Cleavage Reaction and Its Products/ 8.4 Summary/ References/ Part.9: Infl uence of Algal Secondary Metabolites on Plankton Community Structure: 9.1 Introduction/ 9.2 Early Studies/ 9.3 General Considerations/ 9.4 Specific Aspects/ 9.5 Single Metabolites/ 9.6 Conclusions/ References/ Part.10: Herbivore Offense in the Sea: The Detoxifi cation and Transport of Secondary Metabolites: 10.1 Introduction/ 10.2 Proximate Mechanisms of Herbivore Tolerance/ 10.3 Detoxification and Macroalgal-Herbivore Interactions/ 10.4 Using Population-Level Variation in Herbivore Traits as an Analytical Tool/ 10.5 Conclusion/ References/ Part.11: Secondary Metabolite Defenses Against Pathogens and Biofoulers: 11.1 Introduction/ 11.2 Defenses Against Settlement and Attachment/ 11.3 Lethal and Growth-Inhibitory Antimicrobials/ 11.4 Future Perspective and Conclusions/ References/ Part.12: Oxidative Burst and Related Responses in Biotic Interactions of Algae: 12.1 Introduction/ 12.2 Reactive Oxygen Species and Detection Methods/ 12.3 Inducers and Sources of ROS Emission in Biotic Interactions of Marine Algae/ 12.4 Oxidative-Burst-Associated Responses/ 12.5 Functions of the Oxidative Burst in an Ecological Context, the Hallmark of Parasite or Disease Resistance/ 12.6 Conclusions/ References/ Part.13: Defense Strategies of Algae and Cyanobacteria Against Solar Ultraviolet Radiation:13.1 Introduction/ 13.2 Effects of UVR on Algae/ 13.3 Protective Mechanisms to Counteract Harmful UV Effects/ 13.4 Conclusions/ References/ Part.14: Algal Sensory Chemical Ecology: 14.1 Introduction to Sensory Chemical Ecology/ 14.2 Sexual Communication/ 14.3 Chemoattraction to Nutrients/ 14.4 Sensory Ecology of Ulva Spores/ 14.5 Chemical and Physicochemical Modulation of Spore Settlement in Brown Algae/ References/ Index/
* This is the first ever book devoted entirely to the chemical ecology of algae. Algae from both marine and freshwater habitats are covered, as are macroalgae (seaweeds) and microalgae (including phytoplankton). While its main emphasis is on the ecological rather than chemical aspects of the field, the book also includes a unique introductory chapter intended as a primer on algal natural products chemistry for ecologists. It elucidates the roles of chemical defenses in various regions and habitats, of DMSP, oxidative burst responses, and herbivore offense. *
Colegate, S. M. & Molyneux, R. J. ed.
Bioactive Natural Products 3rd ed.
Detection, Isolation, and Structural Determination
CRC Press 2007.12
624 pp.(H)
ISBN 0-8493-7258-5
26,400円
Contents
1.Introduction and Overview/ 2.Detection and Isolation of Bioactive Natural Products/ 3.Nuclear Magnetic Resonance Spectroscopy: Strategies for Structure Determination/ 4.Quantitative NMR of Bioactive Natural Products/ 5.Development and Application of LC-NMR Techniques to the Identification of Bioactive Natural Products/ 6.Determination of the Absolute Configuration of Bioactive Natural Products using Exciton Chirality Circular Dichroism/ 7.Separation of Enantiomeric Mixtures of Alkaloids and their Biological Evaluation/ 8.UV Dereplication of Natural Products Extracts/ 9.Liquid Chromatography-Mass Spectrometry in Natural Product Research/ 10.Application of High-Speed Counter-Current Chromatography to the Isolation of Bioactive Natural Products/ 11.Biosensing Approach in Natural Products Research/ 12.Anticancer Drug Discovery and Development from Natural Products/ 13.Sourcing Natural Products from Endophytic Microbes/ 14.Isolation of Bioactive Natural Products from Myxobacteria/ 15.Naturally-occurring Glycosidase Inhibitors/ 16.Bioassay-Directed Isolation and Identification of Anti-aflatoxigenic/ 17.Constituents of Walnuts/ 18.Bioactive Peptides in Hen Eggs/ 19.Biological Fingerprinting Analysis: Strategy for Screening of Bioactive Compounds in Traditional Chinese Medicines/ 20.Antimalarial Compounds from Traditionally-used Medicinal Plants/ 21.Germination Stimulant in Smoke: Isolation and Identification/ 22.Plant-associated Toxins: Bioactivity-guided Isolation, Elisa and LCMS Detection/ index/
* Following the successful format of the first edition, this volume brings together collective research from many new contributors and emphasizes the rationale behind the successful detection, isolation, and structure determination of specific compounds.
* The text encompasses a diverse range of techniques that can be applied to terrestrial and aquatic sources. It also allows you to understand how source material can be selected to enhance your opportunity to discover and utilize novel bioactive natural products. *
Petersen, F. & Amstutz, R. ed.
Natural Compounds as Drugs Vol.1
Springer-Verlag 2008.2
377 pp.(H)
ISBN 3-7643-8098-5
33,100円
Contents
1.Mother nature's gifts to diseases of man: The impact of natural products on anti-infective, anticholestemics and anticancer drug discovery/ 2.Drug discovery and development with plant-derived compounds/ 3.Evolutionary mechanisms underlying secondary metabolite diversity/ 4.Biodiversity, chemical diversity and drug discovery/ 5.High impact technologies for natural products screening/ 6.Virtual screening for the discovery of bioactive natural products/ 7.Strain improvement for production of pharmaceuticals and other microbial metabolites by fermentation/ 8.Nutritional and engineering aspects of microbial process development/ 9.Natural products from plant cell cultures/
* The use of drug substances derived from plants, fungi, bacteria, and marine organisms has a long tradition in medicine. Together with their derivatives, and synthetic compounds deduced from natural product precursors, they represent a major part of today's pharmaceutical market. Within the fast developing discipline of molecular biology, natural products also play an important role as tool compounds in pathway screening and validation of target identification concepts. They provide innovative opportunities in drug discovery, leading to a detailed understanding of biological pathways and revealing the functions of involved enzymes or receptors. *
Eich, E.
Solanaceae and Convolvulaceae: Secondary Metabolites
Biosynthesis, Chemotaxonomy, Biological and Economic Significance (A Handbook)
（ナス科およびヒルガオ科：二次代謝産物）
Springer-Verlag 2008.2
638 pp.(H)
ISBN 3-540-74540-8
32,200円
Contents
1. Introduction/ 2. Classification and System in Solanales/ 3. Ornithine-Derived Alkaloids/ 4. Tryptophan-derived Alkaloids/ 5. Miscellaneous Alkaloids/ 6. Phenylalanine-derived Metabolites / Phenylpropanoids/ 7. Terpenoids (Isoprenoids)/ 8. Secondary Metabolites Derived from Fatty Acids and Carbohydrates/ References/ Appendix: Color Plates of Solanales Species/ Subject Index/ Taxonomic Index/
* This comprehensive and interdisciplinary handbook provides a bird’s-eye view of two centuries of research on secondary metabolites of the two large Solanales families, Solanaceae and Convolvulaceae.
* A major aim of this book is the individual phytochemical characterization of the Solanales taxa on the species level. Species are integrated into frameworks of traditional and molecular phylogeny-based classifications. This allows a detailed discussion of chemotaxonomic relationships with regard to all taxon levels up to the order. The text is supplemented by 83 superb color photos of Solanales plants. *
Fattousso, E. & Taglialatela-Scafati, O.
Modern Alkaloids
Structure, Isolation, Synthesis and Biology
最新アルカロイド
Wiley-VCH 2007.12
689 pp. (H)
ISBN 3-527-31521-7
34,000円
Contents
Preface Part 1. BIOACTIVE ALKALOIDS: STRUCTURE AND BIOLOGY: 1.Ecological Roles of Alkaloids/ 2.Antitumor Alkaloids in Clinical Use or in Clinical Trials/ 3.Alkaloids and the Bitter Taste/ 4.Capsaicin and Capsaicinoids/ 5.Glycosidase-Inhibiting Alkaloids: Isolation, Structure, and Application/ 6.Neurotoxic Alkaloids from Cyanobacteria/ 7.Lamellarin Alkaloids: Structure and Activity/ 8.Manzamine Alkaloids/ 9.Antiangiogenic Alkaloids from Marine Organisms/ 10.A Typical Class of Marine Alkaloids: Bromopyrroles/ 11.Guanidine Alkaloids from Marine Invertebrates/ Part 2. NEW TRENDS IN ALKALOID ISOLATION AND STRUCTURE ELUCIDATION: 12.Analysis of Tropane Alkaloids in Biological Matrices/ 13.Extraction and LC-MS Analysis of Alkaloids/ 14. 15N NMR Spectroscopy for Structural Assignment of Alkaloids. Illustrative Case-studies/ Part 3. NEW TRENDS IN ALKALOID SYNTHESIS: 15.Progresses in the Synthesis of Hybrid Antitumor Alkaloids/ 16.Synthesis of Alkaloids by Transition Metal Mediated Oxidative Cyclizations/ 17.Camptothecin and Analogues: Structure and Synthetic Efforts/ 18.Solid-phase and Combinatorial Synthesis of Alkaloid Derivatives/ Part 4. NEW TRENDS IN ALKALOID BIOSYNTHESIS: 19.Regulation of Terpenoid Indole Alkaloids Biosynthesis/ 20.Structure and Biosynthesis of Halogenated Alkaloids/ 21.Engineering Biosynthetic Pathways to Generate Indolocarbazole Alkaloids in Microorganisms/ *
* This book presents all important aspects of modern alkaloid chemistry, making it the only work of its kind to offer up-to-date and comprehensive coverage. While the first part concentrates on the structure and biology of bioactive alkaloids, the second one analyzes new trends in alkaloid isolation and structure elucidation, as well as in alkaloid synthesis and biosynthesis. A must for biochemists, organic, natural products, and medicinal chemists, as well as pharmacologists, pharmaceutists, and those working in the pharmaceutical industry. *
El-Sharoud, W. ed.
Bacterial Physiology
A Molecular Approach
（細菌生理学）
Springer-Verlag 2008.1
372 pp.(H)
ISBN 3-540-74920-9
33,000円
Contents
1. Subcellular Organisation in Bacteria/ 2. Molecular Components of the Bacterial Cytoskeleton/ 3. Mechanosensitive Channels: Their Mechanisms and Roles in Preserving Bacterial Ultrastructure During Adaptation to Environmental Changes/ 4. Structural and Functional Flexibility of Bacterial Respiromes/ 5. Protein Secretion in Bacterial Cells/ 6. Regulation of Transcription in Bacteria by DNA Supercoiling/ 7. Quorum Sensing/ 8. Environmental Sensing and the Role of Extracytoplasmic Function Sigma Factors/ 9. Extracellular Sensors and Extracellular Induction Components in Stress Tolerance Induction/ 10. Ribosome Modulation Factor/ 11. The Role of RpoS in Bacterial Adaptation/ 12. Phenotypic Variation and Bistable Switching in Bacteria/ Index/
* The value of this recent knowledge in bacterial physiology is not only restricted to fundamental biology, but it also extends to biotechnology and drug-discovery disciplines where understanding cell behaviour and structure is essential for better exploitation of useful bacteria and effective eradication of harmful ones. *
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