Tollefsbol, T. O. ed.
Biological Aging
Methods and Protocols
Humana Press 2007.1
414 pp.(H)
ISBN 1-58829-658-x
16,800円
Contents
1.Techniques for Analysis of Biological Aging/ 2.Aging Cell Culture: Methods and Observations/ 3.Methods to Detect Biomarkers of Cellular Senescence: The Senescence Associated b-galactosidase/ 4.Methods of Cell Sorting of Young and Senescent Cells/ 5.Telomere Length Analysis/ 6.A Method to Detect DNA Methyltransferase I Gene Transcription In Vitro in Aging Systems/ 7.A Method to Study the Expression of DNA Methyltransferases in Aging Systems In Vitro/ 8.The Chronological Life Span of Saccharomyces Cerevisiae/ 9.Caloric Restriction and Life-Span Determination of Yeast Cells/ 10.Methods of Nutrigenomics and Longevity Studies in Drosophila: Effects of Diets High in Sucrose, Palmitic Acid, Soy or Beef/ 11.Caloric Restriction Mimetics: A Novel Approach for Biogerontology / 12.Extension of Cell Life-Span Using Exogenous Telomerase/ 13.Inducing Cellular Senescence Using Defined Genetic Elements/ 14.Methods of Induction of Cellular Senescence Using Oxidative Stress/ 15.Nuclear Transfer Methods to Study Aging/ 16.Use of Ribozymes in Cellular Aging Research/ 17.Methods of Evaluation of Pharmacological Drugs Effects on Aging and Life Span in Mice/ 18.Identifying Genes that Extend Life-Span Using a High Throughput Screening System/ 19.Application of DNA Microarray Technology to Gerontological Studies/ 20.Detection and Analysis of Somatic Mutations at a LacZ Reporter Locus in Higher Organisms: Application to Mus Musculus and Drosophila Melanogaster/ 21.Subtractive Hybridization Techniques to Study Cellular Senescence/ 22.Mapping Genetic Polymorphisms Affecting Natural Variation in Drosophila Longevity/ 23.Quantitative Trait Locus (QTL) Mapping in Aging Systems/ 24.2D Gel Proteomics: An Approach to Study Age-related Differences in Protein-abundance or -Isoform Complexity in Biological Samples/ 25.Metabolomics in the Study of Aging and Caloric Restriction / Index/
* Several new tools for the analysis of biological aging have been introduced recently, and this volume provides methods and protocols for these new techniques in addition to its coverage of established procedures. The editors have carefully selected only those topics that are considered mainstays of the field or are showing promise in revolutionizing this relatively new science. The three main areas of focus in this cutting-edge compendium of biological aging research are: methods that are basic to understanding the fundamental mechanisms of cellular aging; techniques used to intervene in the aging process; and approaches to analyzing the many molecular processes of biological aging. *
Holliday, R.
Aging: The Paradox of Life
Why We Age
Springer-Verlag 2007.3
134 pp. (H)
ISBN 1-4020-5640-0
6,400円
Contents
Preface.- Author's note.- 1.Longevity.- 2.Body architecture.- 3.Maintenance of the body.- 4.Causes of ageing.- 5.Ancient origins of ageing.- 6.Mice and men.- 7.How many genes?.- 8.Evolution of human longevity.- 9.Myths of life extension.- 10.Doctors' dilemma.- 11.Modulation of longevity.- 12.Ageing and the angels.- 13.Population pressure and warfare.- 14.Dialogue between life and death.- 15.Road to discovery.- 16.Resolution of the paradox.- Selected references.- Acknowledgements.- Glossary.- Index/
* For centuries people have been puzzled by the inevitability of human aging. For most of the second half of the twentieth century aging remained a mystery, or an unsolved biological problem. At the end of the 20th century a remarkable scientific discovery emerged. It was not a single discovery in the usual sense, because it was based on a series of important interconnected insights over quite a long period of time. These insights made it possible for the very first time to understand the biological reasons for aging in animals and man. It can already be said, however, that the many observations and insights that explain aging will not be accepted as established knowledge for a long time. The field is still full of scientists, and non-scientists, who are just happy to go on speculating about the "mystery" of aging. The aim of this book is to dispel ignorance by explaining in non-technical language what are the reasons for aging and the myth of excessive prolongation of life. *
Riddle, D. R. ed.
Brain Aging
Models, Methods, and Mechanisms
Taylor & Francis 2007.3
408 pp. (H)
ISBN 0-8493-3818-2
21,900円
Contents
1.Assessing Cognitive Aging, 2.Quantifying Aging-Related Changes in the Brain, 3.Assessing Functional Changes in the Aging Nervous System, 4.Mechanisms Contributing to Brain Aging, Index/ *
* Brain Aging: Models, Methods, and Mechanisms offers a selective overview of the current research in this rapidly expanding field. A valuable resource for new and established investigators of the aging brain, this volume reviews critical studies of brain aging in new animal models, as well as advances in brain imaging techniques that permit investigations in aging humans with increasingly higher resolution. Detailed discussions link the information from human and animal studies to illustrate a comprehensive picture of the mechanism of aging. Emphasizing normal brain aging rather than pathological degeneration, the text provides an understanding of fundamental age-related changes in the nervous system and the hypothesis driven research into their bases. *
Bush, S.S. & Martin, T.A. ed.
Geriatric Neuropsychology
Practice Essentials
Taylor & Francis 2005.11
576 pp.(H)
ISBN 1-84169-443-6
16,400円
Contents
* The text provides a lifespan developmental approach to neuropsychology. It addresses the many issues in neuropsychological assessment that differ between younger and older adults. It describes the symptoms, neuropathology, diagnostic considerations, and treatment options of common neurological disorders associated with aging. It also addresses special considerations related to geriatric neuropsychology, such as ethical issues, family systems issues, decision-making capacity, cultural consideration, and medical/medication/substance use issues. Additionally, a list of resources for the elderly and their families is also provided. *
Birren, J. E.
Encyclopedia of Gerontology 2nd ed. 2vols
老年医学百科事典 第2版
Academic Press 2006.12
1594 pp.(H) 2vols
ISBN 0-12-370530-4
89,000円
Contents
Abuse and Neglect of Elders/ Accelerated Aging/ Achievement/ Adaptation/ Addiction: General/ Adult Education/ Age Stratification/ Ageism and Discrimination/ Alcohol and Drugs/ Allergic Reactivity in the Elderly/ Andropause/ Anxiety Disorders/ Arthritis and Rheumatic Diseases/ Assessment: Neuropsychological/ Atherosclerosis/ Attention/ Autonomic Nervous System/ Balance, Posture and Gait/ Behavioral Genetics/ Bereavement and Loss/ Bioenergetics/ Body: Composition, Weight, Height and Build/ Brain and Central Nervous System/ Cancer and Age/ Cancer: Breast/ Cardiovascular System/ Careers in Aging/ Caregiving and Caring/ Cell Death/ Cellular Aging: Growth Factors and Cellular Senescence/ Cellular Signal Transduction/ Centenarians/ Cholesterol and Cell Plasma Membranes/ Cognitive-Behavioral Interventions/ Comparative and Cross-Cultural Studies/ Conditioning/ Consumer Behavior/ Creativity/ Crime and Age/ Critical Gerontology/ Cultural and Ethnic Influences on Aging/ Death and Dying/ Decision Making and Everyday Problem Solving/ Delerium/ Dementia Dementia: Alzheimer's/ Demography/ Dental Health/ Depression/ Diabetes/ Diet and Nutrition/ DNA and Gene Expression/ Driving Behavior/ Economics: Society/ Education and Aging/ Emotions/ Endocrine Function and Dysfunction/ Environmental Gerontology/ Epidemiology/ Erectile Dysfunction/ Ethics and Euthanasia/ Ethics and Medical Decision-Making/ Ethnicity and Minorities/ Evolution and Comparative Biology/ Exercise and Physical Activity/ Extracellular Matrix/ Falls/ Frail Elderly/ Disability, Functional Status, and Activities of Daily Living/ Gastrointestinal System: Function and Dysfunction/ Gender Roles/ Generational Differences: Age-Period-Cohort/ Genetics/ Gerontechnology/ Globalization and Aging/ Glycation/ Grandparenthood/ Health Care and Services/ Hearing/ Hematology and Aging/ History of Aging/ History of Gerontology/ Homeostasis, Homeodynamics and Aging/ Hospice/ Housing/ Human Factors Engineering and Ergonomics/ Humor/ Images of Aging/ Immune System/ Information Processing/Cognition / Inhibition/ Intelligence/ International Perspective on Gerontology/ Language and Communication in Aging/ Language Disorders: Aphasia/ Language Disorders: General/ Learning/ Leisure/ Life Course/ Life Events/ Life Expectancy/ Life Review/ Life SatisfactionLife Span Theory/ Literary Representation of Aging/ Loneliness/ Long Term Care/ Longitudinal Studies/ Markers of Aging/ Marriage and Divorce/ Medicare and Medicaid and Economic Policy of Health Care/ Memory/ Memory, Strategies/ Menopause/ Mental Health/ Metabolism: Carbohydrate, Lipid and Protein/ Mid-Life and Later-Life Crises/ Migration/ Mitochondria and Aging/ Mobility and FlexibilityModels of Aging: Invertebrates, Filamentous Fungi, and Yeasts/ Models of Aging: Vertebrates/ Modernization and Aging/ Motor Control/ Narrative and Aging/ Network Analysis/ Neuroimaging (MRI, PET)/ Neuromuscular System/ Neurotransmitters and Neurotrophic Factors/ Obesity / Obsessive Compulsive Disorders/ Organizations On Aging/ Osteoporosis and Aging Related Bone Disorders/ Oxidative Damage (include Anti-Oxidents)/ Pain and Presbyalgos/ Parkinson's Disease/ Perception/ Personality/ Pharmacology/ Physical Therapy and Rehabilitation/ Politics of Aging/ Premature Aging/ Productivity and Age/ Prostate/ Psychological Well-Being/ Reaction Time/ Religion and Spirituality/ Reminiscence/ Renal and Urinary Tract Function/ Research Design and Methods/ Respiratory System/ Retirement / Self Esteem / Self-Concept and Body Image/ Self-Regulation, Health, and Behavior/ Sexuality, Sensuality, and Intimacy/ Skill Acquisition/ Sleep/ Slowing of Aging/ Smell and Taste/ Social Cognition/ Social Networks, Support, and Integration/ Social Security/ Speech and Communication (speech styles)/ Stress: Physiological/ Stroke/ Suicide/ Syncope/ Telomeres/ Theories of Aging: Biological/ Theories of Aging: Psychology/ Theories of Aging: Social/ Thirst and Hydration/ Time: Perceptions and Concepts/ Touch and Proprioception/ Vision/ Volunteer Activity by Older Adults/ Widowhood and Widowerhood/ Wisdom/ Work and Employment: Individual/ Work and Employment: Society/
* Aging is a complex process of change involving influences of a biological, behavioral, social, and environmental nature, all of which are explored in the context of this encyclopedia. The second edition includes all new articles and wholly new coverage of topics that have seen research advances. *
238-18 登録日 07.11.04
