Brockhausen, I.
Glycobiology Protocols
糖鎖生物学プロトコル
Humana Press 2006.10
381 pp.(H)
ISBN 1-58829-553-2
14,800円
Contents
1. Application of Fluorophore-Assisted Carbohydrate Electrophoresis for the Study of the Dolichol Pyrophosphate-Linked Oligosaccharides Pathway in Cell Cultures and Animal Tissues/ 2. Partial Purification of Mannosylphosphorylundecaprenol Synthase From Micrococcus luteus/ 3. Assay of Dolichyl-Phospho-Mannose Synthase Reconstituted in a Lipid Matrix/ 4. O-Mannosylation in Mammalian Cells/ 5. Methods for Analysis of Unusual Forms of O-Glycosylation/ 6. Structural Analysis of Naturally Occurring Sialic Acids/ 7. Nonradioactive Trans-Sialidase Screening Assay/ 8. Structural Determination of O-Glycans by Tandem Mass Spectrometry/ 9. Detailed Structural Analysis of N-Glycans Released From Glycoproteins in SDS-PAGE Gel Bands Using HPLC Combined With Exoglycosidase Array Digestions/ 10. Molecular Modeling of Glycosyltransferases/ 11. β-Galactoside α2,6-Sialyltransferase and the Sialyl α2,6-Galactosyl-Linkage in Tissues and Cell Lines/ 12. Visualizing Intracellular Distribution and Activity of Core2 β(1,6)N-Acetylglucosaminyltransferase-I in Living Cells/ 13. Gene Expression Analysis of Glycosylation-Related Genes by Real-Time Polymerase Chain Reaction/ 14. Analysis of the Glycodynamics of Primary Osteoblasts and Bone Cancer Cells/ 15. Micromethods for the Characterization of Lipid A-Core and O-Antigen Lipopolysaccharide/ 16. Assay for a Galactosyltransferase Involved in the Assembly of the O7-Antigen Repeat Unit of Escherichia coli / 17. High-Throughput Quantitation of Metabolically Labeled Anionic Glycoconjugates by Scintillation Proximity Assay Utilizing Binding to Cationic Dyes/ 18. Quantitative Analysis of Mucins in Mucosal Secretions Using Indirect Enzyme-Linked Immunosorbent Assay/ 19. Molecular Dissection of the Mouse Zona Pellucida: An Electron-Microscopic Perspective Utilizing High-Resolution Colloidal-Gold Labeling Methods/ 20. Soluble Adamantyl Glycosphingolipid Analogs as Probes of Glycosphingolipid Function/ 21. Diagnosis of Krabbe Disease by Use of a Natural Substrate/ 22. In Vitro Assays of the Functions of Calnexin and Calreticulin, Lectin Chaperones of the Endoplasmic Reticulum/ 23. Quantitative Measurement of SelectinﾐLigand Interactions: Assays to Identify a Sweet Pill in a Library of Carbohydrates/ 24. Binding and Inhibition Assays for Siglecs/ *
Sansom, C. & Markman, O.
Glycobiology
Scion Pub. 2007.2
374 pp.(H) 【在庫有り】
ISBN 1-90484-227-5
25,400円
Contents
Sec. 1. Introduction: 1.Half a century at the carbohydrate-protein interface/ 2.Glycobiology - discovery, diagnostics and drugs/ Sec. 2. Synthesis of Carbohydrate and Glycoconjugates: 3.Sugar-lectin interactions: glycotargeting with synthetic glycoconjugates/ 4.Recent developments in the synthesis and application of sialylmimetics/ Sec. 3. Analysis and Structure: 5.Structure and function of the chondroitin/dermatan sulfates/ 6.Revealing the hidden dimensions of glycosaminoglycans in solution and protein complexes with saccharide libraries, FTIR, and SRCD/ 7.S tructural determination of N-linked glycans by matrix-assisted laser desorption/ionization and electrospray ionization mass spectrometry/ 8.Integrated approach to glycan structure-function relationships/ Sec. 4. Cell Biology of Carbohydrates and Glycoproteins: 9.Some observations on the molecular structure and signaling properties of cell surface proteoglycans/ 10.Galectins: effective modulators of cytoskeletal organization and cellular growth - focus on galectin-8 as a model system/ 11.Intracellular lectin involvement in glycoprotein maturation and quality control in the secretory pathway/ Sec. 5. Carbohydrate-Binding Proteins: 12.The diversity of sialic acids and their interplay with lectins/ 13.Structure and carbohydrate specificity of beta -p rism I fold lectins/ 14.Protein-glycan interactions in immunoregulation: galectins as tuners of the inflammatory response/ 15.Recognition of bacterial glycoepitopes by pulmonary C-type lectins as an arm of lung innate immunity/ 16.Selectin and integrin recognition of ligands under shear flow: affinity and beyond/ Sec. Carbohydrate-Modifying Enzymes: 18Complex carbohydrate-modifying enzymes/ 19.Glycosyltransferases specific for the synthesis of mucin-type O-glycans / 20.Glycosylation in development/ Sec. 7. Glycobiology and Medicine: 21.Glycobiology of mucins in the human gastrointestinal tract/ 22.Mucosal glycoconjugates in inflammatory bowel disease and colon cancer/ 23.Selectin-mediated metastasis of tumor cells: Alteration of carbohydrate-mediated cell-cell interactions in cancers induced by epigenetic silencing of glycogenes/ 24.Glycosphingolipids in health and disease/ 25.Pathogen-host interactions in Entamoeba histolytica/ Sec. 8. Industrial Glycobiology: 26.The development of iminosugars as drugs/ 27.Carbohydrate biosensors/ 28.Glycoanalysis on a lectin array: application to the development of biopharmaceuticals and life science research/ 29.Lectin chips and CarboDeep '99: a rapid carbohydrate fingerprinting technology and its application for the food scientists/ Afterword (Nathan Sharon)/ *
Dodziuk, H. ed.
Cyclodextrins and Their Complexes
Chemistry, Spectroscopy and Applications
シクロデキストリンハンドブック
Wiley -VCH 2006.11
504 pp.(H)
ISBN 3-527-31280-3
24,000円
Contents
* 本書はシクロデキストリンに関する最新のノウハウを豊富に収録し、分子認識からシクロデキストリンの酵素モデルとしての利用まで、幅広い内容を一冊にまとめています。
* 各章では反応性や化学性、クロマトグラフィー、X線、NMRなどの物理化学的分析法に加え、モデル計算、ロタキサン・カテナン構造、製薬産業での応用などをまとめています。そのほか、化粧品やトイレタリー、繊維や梱包材料、農薬、電気化学センサーやデバイスなどの応用事例も取り上げています。
Contents List of Contributors/ 1 Molecules with Holes ﾐ Cyclodextrins/ 2 Modification Reactions of Cyclodextrins and the Chemistry of Modified Cyclodextrins/ 3 Polymers Involving Cyclodextrin Moieties/ 5 Chromatographic Studies of Molecular and Chiral Recognition/ 6 The Application of Cyclodextrins for Enantioseparations/ 7 Crystallographic Study of Cyclodextrins and Their Inclusion Complexes/ 8 Microcalorimetry/ 9 NMR of Cyclodextrins and Their Complexes/ 10 Other Physiochemical Methods/ 11 Modeling of CyDs and Their Complexes/ 12 Rotaxane and Catenane Structures Involving Cyclodextrins/ 13 Large-ring Cyclodextrins/ 14 Pharmaceutical Applications of Cyclodextrins and Their Derivatives/ 15 Cyclodextrins in Dispersed Systems/ 16 Applications Other Than in the Pharmaceutical Industry/ Index/ *
Billiaderis, C. G. & Izydorczyk, M.S.
Functional Food Carbohydrates
CRC Press 2006.10
570 pp. (H)
ISBN 0-8493-1822-x
19,400円
Contents
1.Cereal β-Glucans : Structures, Physical Properties, and Physiological Funcitons / 2.Resistant Starch. / 3.Konjac Glucoman./ 4.Seed Polysaccharide Gums./ 5.Microbial Polysaccharides./ 6.Chitosan as a Dietary Supplement and a Food./ 7.Arabinoxylans:Technologically and Nutritionally Functional Plant Polysaccharides./ 8.Carbohydrates and the Risk of Cardiovascular Disease./ 9.Carbohydrates and Obesity./ 10.Dietary Carbohydrates and Risk of Cancer./ 11.The Role of Carbohydrates in the Prevention and Management of Type 2 Diabetes./ 12.Carbohydrates and Mineral Metabolism./ 13.Dietary Carbohydrates as Mood and Performance Modulators./ 14.Carbohydrates and Gastrointestinal Tract Funciton./ 15.Probiotics, Prebiotics, and Sunbiotics : Functional Ingredients for Microbial Management Strategies./ 16.Potential Use of Carbohydrates as Stabilizers and Delivery Vehicles of Bioactive Substnces in Foods. / 17.Food Regulations : Health Claims for Foods Fortified with Carbohydrates or Other Nutraceuticals./ Index. *
Fukuda, M. ed.
Glycomics
Methods in Enzymology Vol. 416
Academic Press 2006.10
456 pp. (H)
ISBN 0-12-182821-2
20,700円
Contents
Section 1 - Carbohydrate-Protein Interactions-Physical Measurements/ Section 2 V Phage Display Library/ Section 3 - Glycosyltransferase Expression Profiling/ Section 4 - CHO mutants in Glycan Biosynthesis/ Section 5 - Function of Sulfation/ Section 6 - Functions Revealed by Forced Expression or Gene Knockout/
* In the past decade, there has been an explosion of progress in understanding the roles of carbohydrates in biological systems. This explosive progress was made with the efforts in determining the roles of carbohydrates in immunology, neurobiology and many other disciplines, examining each unique system and employing new technology. This volume represents the second of three in the Methods in Enzymology series, including Glycobiology (vol. 415) and Functional Glycomics (vol. 417), dedicated to disseminating information on methods in determining the biological roles of carbohydrates.The methods covered include structural analysis of carbohydrates, biological and chemical synthesis of carbohydrates, expression and determination of ligands for carbohydrate-binding proteins, gene expression profiling including micro array, and generation of gene knockout mice and their phenotype analyses. *
324-2 登録日 07.04.01
