Perdew, G. H. et al.
Regulation of Gene Expression
Molecular Mechanisms
Humana Press 2006.9
344 pp.(H)
ISBN 1-58829-265-7
14,500円
Contents
Part I. Gene Expression Control at the mRNA Level: 1. Overview/ 2. Messenger RNA Accumulation/ 3. Transcript Profiling/ 4. Transcriptional Regulation of Gene Expression/ 5. Posttranscriptional Processing of Messenger RNA/ Study Questions/ References/ Part II. Regulation of Protein Levels and Transcription Factor Function: 1. Overview/ 2. Protein Synthesis and Turnover/ 3. Proteomics/ 4. Determination of Protein-Protein Interactions and the Motifs That Mediate Them/ 5. Posttranslational Modifications/ 6. Dissection of Signaling Pathways/ Study Questions/ References/ Part III. Use of Transgenic and Knockout Mice to Study Gene Regulation: 1. Overview/ 2. Production of Transgenic Animals/ 3. Knockout Animals/ 4. Isolation of Cells and Cell Lines From Transgenic and Knockout Animals/ Study Questions/ References/ Index/ *
Avison, M.
Measuring Gene Expression
Taylor & Francis 2006.7
328 pp.(P)
ISBN 0-415-37472-3
9,800円
Contents
1. Gene Expression and its Control 2. RNA Isolation and Analysis 3. Hybridization-based Methods for Measuring Transcript Levels 4. PCR-based Methods for Measuring Transcript Levels 5. Differential Display, Subtractive Hybridization, Amplification Suppression and SAGE Techniques for Measuring Gene Expression 6. Measuring Gene Expression Using Reporter Gene Assays 7. Analysis of the Proteome 8. Statistical Analysis of Gene Expression Data /
* In the post-genomic age, much biomedical research looks at when, where, and at what level genes are expressed. Measuring Gene Expression is an all-in-one introduction to the main methods of measuring gene expression, including RT-PCR, differential display, RNA interference, reporter genes, microarrays, and proteomics, as well asa section on RNA isolation and analysis. Thereis an overview of each method: its pros and cons, sample preparation, sources of error, and data interpretation. *
Ferreira, C.
Gene Expression Programming 2nd ed.
Mathematical Modeling by an Artificial Intelligence
Springer-Verlag 2006.
478 pp. (H)
ISBN 3-540-32796-7
21,200円
Contents
1.The Biological Perspective.- 2.The Entities of Gene Expression Programming.- 3.The Basic Gene Expression Algorithm.- 4.The Basic GEA in Problem Solving.- 5.Numerical Constants and the GEP-RNC Algorithm.- 6.Automatically Defined Functions in Problem Solving.- 7 Polynomial Induction and Time Series Prediction.- 8.Parameter Optimization.- 9.Decision Tree Induction.- 10.Design of Neural Networks.- 11.Combinatorial Optimization.- 12.Evolutionary Studies/
* Author thoroughly describes the basic ideas of gene expression programming (GEP) and numerous modifications to this powerful new algorithm. This monograph provides all the implementation details of GEP so that anyone with elementary programming skills will be able to implement it themselves. *
Rossi, J. ed.
MicroRNA Methods
Methods in Enzymology Volume 427
Academic Press 2007.8
304 pp. (H)
ISBN 0-12-373917-9
20,100円
Contents
SECTION I. Identifying Micro RNAs and their targets Chapter 1: Identification of viral miRNAs Chapter 2: Robust machine learning algorithms predict microRNA genes and targets Chapter 3: Idenfication of virally encoded microRNAs Chapter 4: Computational Methods for microRNA Target Prediction SECTION II. Micro RNA expression, maturation and functional analysis Chapter 5: In vitro and in vivo assays for the activity of the Drosha-DGCR8 complex Chapter 6: Microarray analysis of microRNA gene expression. Chapter 7: Cloning and detecting signature microRNAs from mammalian cells Chapter 8: Approaches for studying microRNA and small interfering RNA methylation in vitro and in vivo Chapter 9: Analysis of small RNA profiles during development. Chapter 10: Dissecting MicroRNA-mediated Gene Regulation and Function in T Cell Development SECTION III. MiRNAs and Disease Chapter 11: Investigation of microRNAs alterations in leukemias and lymphomas Chapter 12: Discovery of pathogen-regulated small RNAs in plants Chapter 13: Protocols for expression and functional analysis of viral microRNAs *
Wells, K. D.
The Ecology and Behavior of Amphibians
両生類の生態と習性
University of Chicago Press 2007.10
1400 pp. (H)
ISBN 0-226-89334-0
10,500円
Contents
* Consisting of more than six thousand species, amphibians are more diverse than mammals and are found on every continent save Antarctica. Despite the abundance and diversity of these animals, many aspects of the biology of amphibians remain unstudied or misunderstood. The Ecology and Behavior of Amphibians aims to fill this gap in the literature on this remarkable taxon. It is a celebration of the diversity of amphibian life and the ecological and behavioral adaptations that have made it a successful component of terrestrial and aquatic ecosystems.
* Synthesizing seventy years of research on amphibian biology, Kentwood D. Wells addresses all major areas of inquiry, including phylogeny, classification, and morphology; aspects of physiological ecology such as water and temperature relations, respiration, metabolism, and energetics; movements and orientation; communication and social behavior; reproduction and parental care; ecology and behavior of amphibian larvae and ecological aspects of metamorphosis; ecological impact of predation on amphibian populations and antipredator defenses; and aspects of amphibian community ecology. With an eye towards modern concerns, The Ecology and Behavior of Amphibians concludes with a chapter devoted to amphibian conservation. *
Sambrook, J.
The Condensed Protocols from Molecular Cloning
A Laboratory Manual
モレキュラー・クローニング プロトコル要約集
Cold Spring Harbor Laboratory 2006.5
800 pp.(P)
ISBN 0-87969-771-7
15,000円
Contents
* 本書は全3巻で刊行され、絶大な評価を得て世界の分子生物学研究者に利用されているプロトコル集 "Molecular Cloning: A laboratory Manual 3rd ed." の要約版です。
* 実験室での利用を想定し、全3巻のオリジナルをプロトコルの具体的な手順のみに内容を絞り込んで１巻にまとめ、付録のデータにはオリジナルから重要なものを選んで収録しています。各プロトコルにはオリジナルの該当ページへの参照が記載されており、オリジナルとの併用にも便利です。
Contents: 1.Using Plasmid Vectors in Molecular Cloning/ 2.Bacteriophage λand Its Vectors/ 3.Working with Bacteriophage M13 Vectors/ 4.Working with High-Capacity Vectors/ 5.Gel Electrophoresis of DNA and Pulsed-Field Agarose Gel Electrophoresis/ 6.Preparation and Analysis of Eukaryotic Genomic DNA/ 7.Extraction, Purification, and Analysis of mRNA from Eukaryotic Cells/ 8.In Vitro Amplification of DNA by the Polymerase Chain Reaction/ 9.Preparation of Radiolabeled DNA and RNA Probes/ 10.Working with Synthetic Oligonucleotide Probes/ 11.Preparation of cDNA Libraries and Gene Identification/ 12.DNA Sequencing/ 13.Mutagenesis/ 14.Screening Expression Libraries/ 15.Expression of Cloned Genes in Escherichia Coli/ 16.Introducing Cloned Genes into Cultured Mammalian Cells/ 17.Analysis of Gene Expression in Mammalian Cells/ 18.Protein Interaction Technologies/ Appendices/ Index/ *
Schatten, G.P. ed.
Current Topics in Developmental Biology Vol. 78
Academic Press 2007.2
288 pp (H)
ISBN 0-12-373748-6
21,400円
Contents
Chapter 1 Contribution of Membrane Mucins to Tumor Progression through Modulation of Cellular Growth Signaling Pathways/ Chapter 2 Regulation of the Epithelial Sodium Channel by Peptidases/ Chapter 3 Advances in Defining Regulators of Cementum Development and Periodontal Regeneration/ Chapter 4 Anabolic agents and the BMP pathway/ Chapter 5 The role of mammalian circadian proteins in normal physiology and genotoxic stress responses/ Chapter 6 Autophagy and Cell Death/ *
Schatten, G.
Current Topics in Developmental Biology Vol. 80
Academic Press 2007.10
402 pp. (H)
ISBN 0-12-373914-4
21,400円
Contents
1 Similarities Between Angiogenesis and Neural Development: What Small Animal Models Can Tell Us/ 2 Junction restructuring and spermatogenesis: the biology, regulation, and implication in male contraceptive development/ 3 Substrates of the Methionine Sulfoxide Reductase System and Their Physiological Relevance/ 4 Organic anion transporting polypeptides at the blood-brain and blood-cerebrospinal fluid barriers/ 5 Mechanisms and evolution of environmental responses in Caenorhabditis elegans/ 6 Molluscan shell proteins: primary structure, origin and evolution / 7 Pathophysiology of the blood-brain barrier: animal models and methods/ 8 Genetic manipulation of megakaryocytes to study platelet function/ 9 Genetics and Epigenetics of the Multifunctional Protein CTCF/ *
43-33 登録日 07.10.14
