Muir, T. W.
Non-Natural Amino Acids
Methods in Enzymology Vol.462
Academic Press 2009.8
312 pp.(H)
ISBN 0-12-374310-9
21,200円
Contents
1. Protein Engineering with the Traceless Staudinger Ligation/ 2. Mechanistic studies of RNR using unnatural amino acids and semisynthesis/ 3. Using Expressed Protein Ligation to Probe the Substrate Specificity of Lantibiotic Synthetases/ 4. Protein Phosphorylation by Semisynthesis: From Paper to Practice/ 5. Mechanistic studies of semisynthetic ion channels/ 6. Semi-synthesis of proteins using split inteins/ 7. Segmental Isotopic Labeling of Proteins for Nuclear Magnetic Resonance/ 8. Use of intein-mediated protein ligation strategies for the fabrication of functional protein arrays/ 9. Expressed Protein Ligation for Metalloprotein Design and Engineering/ Index/ *
Schafer, H. A. & Wohlbier , L. M.
Diamino Amino Acids
Nova Science Pub. 2008.10
256 pp.(H)
ISBN 1-60456-892-5
12,900円
Contents
Part.1: Research and Review Studies: 1.Asymmetric Dimethyl L-arginine (ADMA) and Delayed Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage(aSAH)/ 2.D-Serine and Schizophrenia/ 3.Analysis of Methylated Arginines by High-Performance Liquid Chromatography-Florescence detection: A Review/ 4.Yield of Compatible Solute Hydroxyectoine through Conversion from Ectoine by Recombinant Escherichia Coli/ 5.Significant Yield of Ectoine by Halomonas sp. EG6 during Osmotic Downshock Treatment/ 6.Increase in Amino Acids and Ammonia During Liquefaction of Semen/ 7.Selected Diamino Acids in Soils of Differently Managed Mountain Meadow and Forest Ecosystems: Assessment of their Role in the Ecosystem Nutrition/ Part.2: Short Communication: 8.Arginine Conserves the Hemostasis Activation State of Plasma Even Against Freezing/Thawing/ Index/
* Book Description: Diamino Amino Acids are one of the 12 groups of amino acids.Amino Acids are the chemical units or "building blocks" of the body that make up proteins. Protein substances make up the muscles, tendons, organs, glands, nails, and hair. Growth, repair and maintenance of all cells are dependent upon them. Next to water, protein makes up the greatest portion of our body weight. Amino Acids that must be obtained from the diet are called "Essential Amino Acids" other Amino Acids that the body can manufacture from other sources are called "NonEssential Amino Acids." *
Konno, R. et al. ed.
D-Amino Acids: Practical Methods and Protocols, Vol.1
Analytical Methods for D-Amino Acids
Nova Science Pub. 2009.7
(H)
ISBN 1-60741-376-0
21,000円
Contents
1.Chromatographic Determination of Free D- and L-Amino Acids in Marine Algae/ 2.Determination of Acidic D-Amino Acids and their N-Methyl Derivatives in Bivalves and other Mollusks/ 3.Purification and Determination of N-Methyl-d-Aspartic Acid (NMDA) in Biological Tissues/ 4.A Sensitive One Step HPLC Method for Simultaneous Determination of N-Methyl-(D and L)-Aspartate, N-Methyl-(D and L)-Glutamate and (D and L)-Aspartate in Biological Tissues/ 5.Methods for Total Determination of D-Aspartic Acid, D-Glutamic Acid and N-Methyl-D-Aspartic Acid and for the Specific Determination of D-Aspartic Acid/ 6.An Improved HPLC Method for Determination and Quantification of D- and L-Aspartic Acid/ 7.Determination of Free D-Aspartate and D-Serine in Rat Brain and Periphery by Gas/ Chromatography and High-Performance Liquid Chromatography/ 8.An LC Method for the Analysis of d-Amino Acids/ 9.Sensitive Determination of d-Amino Acids in Rat Brain by HPLC with a Pirkle-Type Chiral Column, Following Precolumn Fluorescence Derivatization with NBD-F/ 10.Determination of Small Amounts of D-Amino Acids in Mammals using Column-Switching HPLC/ 11.Sensitive Determination of Amino Acid Enantiomers by CE/LIF/ 12.Methods of Detection for Amino Acid Enantiomers in the Vertebrate Retina/ 13.Determination of NG-Nitro-Arginine Enantiomers in Rat Plasma by Capillary Electrochromatography with a Chiral Mobile Phase/ 14.Determination of D-Enantiomers in Amino Acid Mixtures and Peptides Subjected to Sequencing/ 15.Quantitative Determination of the Protein of Bacterial Origin Based on D-Amino Acid Contents/ 16.Methods for Detection of d-Amino Acids using D-Amino Acid Oxidase/ Index/
* D-Amino acids are stereoisomers or optical isomers of naturally occurring L-amino acids. D Amino acids and L-amino acids have almost the same physical and chemical properties. D-Amino acids have been considered to be unnatural substances that are produced only when we synthesize amino acids in laboratories or factories. Indeed, equal amounts of D-amino acids and L-amino acids (racemic mixture) are produced by chemical synthesis. Until recently, living organisms were thought to contain exclusively L-amino acids. Before the emergence of life, D- and L-amino acids should have existed on the primitive earth, because amino acids are considered to be produced under the conditions of high temperature, high pressure and lightning. *
Konno, R. et al. ed.
D-Amino Acids: Practical Methods and Protocols, Vol.2
Free D-Amino Acids
Nova Science Pub. 2009.7
(H)
ISBN 1-60741-377-9
21,000円
Contents
1.A Systematic Approach to the Brain D-Serine System/ 2.Immunohistochemical Study of D-Serine/ 3.Immunohistochemistry for D-Serine in Brain/ 4.Brain Slice Preparation for Evaluation of the Pathophysiological Functions of D-Serine/ 5.Nephrotoxicity of D-Serine in Rats/ 6.Preparation of a Polyclonal Antiserum against D-Aspartate/ 7.Vesicular Storage in and Secretion of D-Aspartate from Neuroendocrine Cells/8.D-Aspartate in Frog Harderian Gland/ 9.The Endocrine Regulation of the Testis is mediated by D-Aspartic Acid: A Study in the Lizard Podarcis S. Sicula / 10.D-Aspartic Acid in the Nervous System of a Mollusc: An Immunohistochemical Protocol/ 11.Analysis, Distribution, and Physiological Functions of Free D-Alanine in Aquatic Invertebrates/ 12.D-Glutamic Acid Induced Muscle Contraction in Silkworm Larva/ 13.Primary Study of D-Amino Acid Accumulation System/ 14.D-Amino Acids and Immune Response/ 15.Considerations for the use of 'Rapid' Cell Superfusion and Voltage Clamp to Investigate the Role of Rare Amino Acids in Synaptic Transmission/ 16.Are D-Amino Acids Prevalent among Eukaryotes?/ 17.Nutritional Evaluation of D-Amino Acids/ 18.D-Amino Acids in Food/ 19.D-Amino Acid Determination in Foods, Beverages, and Biological Samples/ 20.Gas Chromatographic Determination of D-Amino Acids in Food and Beverages/ Index/
* It is an interesting and important question why D-amino acids were eliminated and organisms have evolved using only L-amino acids. This mystery has not been solved. D-Amino acids have been considered exceptional amino acids that exist only in prokaryotes and a part of lower organisms. However, the development and improvement of analytical instruments and methods have revealed that D-amino acids are present in organisms far more in the amount and extent than previously considered. It has become clear that D-amino acids are present in invertebrates and vertebrates including humans and that some of D-amino acids have important physiological functions. Biological systems for synthesis and degradation of D-amino acids have also been found.Volume 1 is dedicated to analytical methods for D-Amino acids. *
Konno, R. et al. ed.
D-Amino Acids: Practical Methods and Protocols, Vol.3
D-Amino Acids in Peptides and Proteins
Nova Science Pub. 2009.7
(H)
ISBN 1-60741-378-7
21,000円
Contents
1.An Essay on D-Amino Acids: Retrospection and Perspective/ 2.Detection of the Specific D-Aspartic Acid Residues in Protein/ 3.Detection of Amyloid Beta-Peptides with L-Isoaspartate in Alzheimer's Disease/ 4.Detection of D-Amino Acid in Peptides by RP-HPLC and Mass Spectrometry/ 5.Determination of D-Amino-Acid Residues in Peptides from Animal Venom by NMR: Application to Platypus Venom Peptide OvCNPs/ 6.Protein L-Isoaspartyl-O-Methyltransferase Catalyzes in situ Formation of D-Aspartate and D-Isoaspartate in Proteins/ 7.Purification of a Novel Mammalian Proteinase for D-Aspartate-Containing Protein, D-Aspartyl Endopeptidase (DAEP)/ 8.Micro-Purification and Structural Assay of Poly-Gamma-Glutamate, a D-Amino Acid-Containing Biopolymer/ 9.Estimation of Chronological Age using the Aspartic Acid Racemization Method on Dentin Samples/ 10.The Use of D-Amino Acids in Peptide Design/ 11.Cellular Approach of the Biogenesis of D-Amino-Acid Containing Peptides in Eukaryotes: The Crustacean Model/ 12.Detection Of D-Beta-Asp Containing Proteins in Paraffin-Embedded Ocular Samples Using Anti-D-Beta-Asp Containing Protein Antibodies/Index/
*
Konno, R. et al. ed.
D-Amino Acids: Practical Methods and Protocols, Vol.4
Enzymes Involved in the Metabolism of D-Amino Acids
Nova Science Pub. 2009.7
(H)
ISBN 1-60741-379-5
21,000円
Contents
1.Purification of Alanine Racemase from Helicobacter pylori/ 2.Disruption of Alanine Racemase Gene of Schizosaccharomyces pombe/ 3.Assay Method for Aspartate Racemase Activity by HPLC/ 4.Serine Racemase of Silkworm, Bombyx mori/ 5.Recombinant Serine Racemase Preparation/ 6.D-Amino Acid Oxidase Activity Assays/ 7.Histochemical Detection of D-Amino-Acid Oxidase Activity in Rat Brain/ 8.Evaluation of Chiral Inversion of D-Amino Acid by Stable Isotope Methodology/ 9.Engineering the Substrate Specificity of D-Amino Acid Oxidase by Rational and Directed Evolution Methods/ 10.Transformation of Plants with D-Amino Acid Resistance Selectable Markers/ 11.Screening for Mutant Mice Lacking D-Amino-Acid Oxidase Activity/ 12.Astroglial Expression of D-Amino Acid Oxidase: Regional and Cell-Type Specific Expression/ 13.D-Amino Acid Oxidase: A Versatile Tool to Study the Function of the Glial-Derived Neuromodulator D-Serine at Glutamatergic Synapses/ 14.Resonance Raman Study on Charge-Transfer Complexes of Porcine D-Amino Acid Oxidase/ 15.Immunodetection of D-Aspartate Oxidase/ 16.High-Performance Liquid Chromatographic Determination of D-Aspartate Oxidase Activity in Rat Tissues/ 17.Cloning of the Human Brain D-Aspartate Oxidase cDNA and its Expression in Escherichia coli/ 18.Methods for N-Acyl-d-Amino Acid Amidohydrolase Research/ 19.Activity Measurement of Hydantoin Racemase Enzyme: A Key for the Production of Optically Pure D-Amino Acids/ 20.Enzymes Acting on D-Amino Acid Amides/ 21.Activity on D-Tryptophan Attributable to Trivial Conformational Change of Trypotphanase in Highly Concentrated Ammonium Phosphate Solution/ Index/
*
Davies, J. S. ed.
Amino Acids, Peptides And Proteins Vol.36
Royal Society of Chemistry 2007.12
400 pp.(H)
ISBN 0-85404-252-0
60,700円
Contents
1.Amino acids/ 2.Peptide synthesis/ 3.Analogue and conformational studies on peptides, hormones and other biologically active peptides/ 4.Cyclic, modified and conjugated peptides/ 5.Metal complexes of amino acids and peptides/ Index/
* In an ever-increasing domain of activity, Amino Acids, Peptides and Proteins provides an annual compilation of the world's research effort into this important area of biological chemistry. *
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