Meyers, R. A. ed.
Proteins Vol.1 & 2
From Analytics to Structural Genomics
タンパク質：分析から構造ゲノミクスまで 全2巻
Wiley -VCH 2006.12
1218 pp.(H) 2 vols set
ISBN 3-527-31608-6
56,800円
Contents
* 本書は全16巻の百科事典 ﾒEncyclopedia of Molecular Cell Biology and Molecular Medicineﾓからタンパク質研究に関わる記事をまとめたリファレンスです。
* 3人のノーベル賞受賞者が寄稿しており、タンパク質の構造、モデリング、発現、分析などタンパク質研究の幅広いトピックをまとめています。
Contents:
VOLUME 1
Pt.1.Structure and Function : 1.Macromolecules, X-Ray Diffraction of Biological/ 2.Protein NMR Spectroscopy/ 3.Electron Microscopy of Biomolecules/ 4.Circular Dichroism in Protein Analysis/ 5.Protein Structure Analysis: High-throughput Approaches/ 6.Aggregation, Protein/ 7.Prions/ 8.Alzheimerﾕs Disease/ 9.Chaperones, Molecular/ 10.Motor Proteins/ 11.DNA-Protein Interactions/ Pt.2.Modelling and Design : 12.Protein Modeling/ 13.Synthesis of Peptide Mimetics and their Building Blocks/ 14.Design and Application of Synthetic Peptides/ 15.Synthetic Peptides: Chemistry, Biology, and Drug Design/ Pt.3.Expression, Synthesis and Degration : 16.Ribosome, High Resolution Structure and Function/ 17.Ubiquitin-Proteasome System for Controlling Cellular Protein Levels/ 18.Plant-based Expression of Biopharmaceuticals/ 19.Cell-free Translation Systems/
VOLUME 2
Pt.1.Analytical Techniques : 1.HPLC of Peptides and Proteins/ 2.Protein Purification/ 3.Gel Electrophoresis, 2D-Difference/ 4.Proteomics/ 5.Mass Spectrometry-based Methods of Proteome Analysis/ 6.Protein Microarrays/ 7.Informatics (Computational Biology)/ 8.Nucleic Acid and Protein Single Molecule Detection and Characterization/ 9.Footprinting Methods to Examine the Structure and Dynamics of Proteins/ Pt.2.Signalling and Regulation : 10.Biological Regulation by Protein Phosphorylation/ 11.Intracellular Signaling in Cancer/ 12.Receptor Biochemistry/ 13.Signal Transduction Mediated by Heptahelical Receptors and Heterotrimeric G Proteins/ 14.Growth Factors/ 15.Cytokines: Interleukins/ 16.Viral Inhibitors and Immune Response Mediators: The Interferons/ 17.Molecular Mediators: Cytokines/ * With three Nobel Laureates contributing to this invaluable collection of high-quality articles, carefully selected from the highly praised R.A. Meyer's Encyclopedia, these two volumes cover a wide range of topics in protein research. Clearly divided into sections on structure, modeling, expression, analysis and others, the chapters are designed to aid readers of all levels of expertise. Each chapter includes a glossary of the most important keywords, a concise summary of the article concerned and comprehensive references for further reading. Similarly, the uniform structure of the articles makes them very easy to use, resulting in a ready reference for molecular and cell biologists, biochemists, biophysicists, and biotechnologists, as well as those working in the pharmaceutical and biotechnological industries. *
Bargon, J. & Kuhn, L. T. ed.
In situ NMR Methods in Catalysis
Springer-Verlag 2007.7
169 pp. (H)
ISBN 3-540-71426-X
25,000円
Contents
1. Homogeneous Catalysis in Ionic Liquids.- 2. Transfer of Parahydrogen-Induced Hyperpolarization to Heteronuclei.- 3. Investigations in Supercritical Fluids.- 4. Continuous Asymmetric Hydrogenation.- 5. Exploiting Nuclear Spin Polarization to Investigate Free Radical Reactions via in situ NMR
* So much is covered here in critical review, from the present position of developing research to future trends, that this book will still be an indispensable text ten years from now. The text is also available online at www.springerlink.com. *
Arrondo, J. L.R & Alonso, A. ed.
Advanced Techniques in Biophysics
Springer-Verlag 2006.
280 pp. (H)
ISBN 3-540-30700-1
23,200円
Contents
1. Protein Nanocrystallization / 2. Differential Scanning Calorimetry of Proteins: an Overview and Some Recent Developments / 3. IR Reflectance Absorbance Studies of Peptide Structure, Orientation, and Conformational Flexibility in Langmuir Films: Relevance for Models of Pulmonary Surfactant Action / 4. Two-Dimensional Infrared Correlation Spectroscopy / 5. NMR Spectroscopy of Large Biological Macromolecules in Solution / 6. Emerging Techniques in Fast Multidimensional NMR / 7. Principles and Application of Projected Multidimensional NMR Spectroscopy G-matrix Fourier Transform NMR / 8. Protein Nanomechanics as Studied by AFM Single-Molecule Force Spectroscopy / 9. Multiphoton-Excitation Fluorescence Microscopy and Membranes / 10. Three-Dimensional Electron Microscopy. The Coming of Age of a Versatile Structural Biology Technique / Subject Index / *
Serdyuk, I. N. et al.
Methods in Molecular Biophysics
Structure, Dynamics, Function
（分子生物物理学における手法）
Cambridge University Press 2007.3
1136 pp. (H)
ISBN 0-521-81524-x
15,000円
Contents
Foreword; Preface; 1. Biological macromolecules and physical tools; 2. Mass spectroscopy; 3. Thermodynamics; 4. Hydrodynamics; 5. Optical spectroscopy; 6. Optical microscopy; 7. X-ray and neutron diffraction; 8. Electron diffraction; 9. Molecular dynamics; 10. Nuclear magnetic resonance; References. *
* Our knowledge of biological macromolecules and their interactions is based on the application of physical methods, ranging from classical thermodynamics to recently developed techniques for the detection and manipulation of single molecules. These methods, which include mass spectrometry, hydrodynamics, microscopy, diffraction and crystallography, electron microscopy, molecular dynamics simulations, and nuclear magnetic resonance, are complementary; each has its specific advantages and limitations. Organised by method, this textbook provides descriptions and examples of applications for the key physical methods in modern biology. *
Messerschmidt, A.
X-Ray Crystallography of Biomacromolecules
A Practical Guide
（生体高分子のX線結晶学）
John Wiley & Sons 2007.3
318 pp. (H)
ISBN 3-527-31396-6
19,200円
Contents
Preface. Part I Principles and Methods. 1. Introduction./ 2. Experimental Techniques./ 3. Principles of X-Ray Diffraction by a Crystal./ 4. Diffraction Data Evaluation./ 5. Methods for Solving the Phase Problem./ 6. Phase Improvement by Density Modification and Phase Combination./ 7. Model Building and Refinement./ 8. Crystal Structure Determination of the Time-Course of Reactions and of Unstable Species./ 9. Structural Genomics. Part II Practical Examples. 10. Data Evaluation./ 11. Determination of Anomalous Scatterer or Heavy Atom Positions./ 12. MIRAS and MAD Phasing with the Program SHARP./ 13. Molecular Replacement./ 14. Averaging about Non-Crystallographic Symmetry (NCS) for 4-BUDH./ 15. Model Building and More./ Subject Index. *
Webb, G. ed.
Annual Reports on NMR Spectroscopy Vol. 60
Academic Press 2007.3
245 pp. (H9
ISBN 0-12-505460-2
27,000円
Contents
1. Low Temperature Solid-State NMR Spectroscopy. A Strategy for the Direct Observation of Quadrupolar Nuclides of Biological Interest (P.D. Ellis, A.S. Lipton). 2. NMR methods for Characterising ligand-receptor and drug-membrane interactions in pharmaceutical research (D.A. Middleton). 3. Recent Advances in NMR Studies of Cyclophanes (L. Ernst). 4. Applications of solid-state 31P NMR spectroscopy (A. Iuga et al.). 5. Applications of REDOR for Distance Measurements in Biological Solids (S.L Grage, A. Watts). *
Schalley, C. ed.
Analytical Methods in Supramolecular Chemistry
超分子化学の分析手法
Wiley -VCH 2007.3
502 pp. (H)
ISBN 3-527-31505-5
23,400円
Contents
Preface. / List of Contributors. / 1. Introduction. / 2. Determination of Binding Constants. / 3. Isothermal Titration Calorimetry in Supramolecular Chemistry. / 4. Extraction Methods. / 5. Mass Spectrometry and Gas Phase Chemistry of Supramolecules. / 6. Diffusion NMR in Supramolecular Chemistry. / 7. Photophysics and Photochemistry of Supramolecular Systems. / 8. Circular Dichroism Spectroscopy. / 9. Crystallography and Crystal Engineering. / 10. Scanning Probe Microscopy. / 11. The Characterization of Synthetic Ion Channels and Pores. / 12. Theoretical Methods for Supramolecular Chemistry. / Index. *
* An overview of the techniques used to examine supramolecular aggregates from a methodological point of view. Edited by a rising star in the community and an experienced author, this is a definitive survey of useful modern analytical methods for understanding supramolecular chemistry, from NMR to single-molecule spectroscopy, from electron microscopy to extraction methods. A definitive study of this field touching many interdisciplinary areas such as molecular devices, biology, bioorganic chemistry, material science, and nanotechnology. *
Sem, D. S.
Spectral Techniques In Proteomics
CRC Press 2007.3
464 pp. (H)
ISBN 1-57444-580-4
21,200円
Contents
Part 1. The Scope of Proteomic and Chemical Proteomic Studies. 1.The Systems-Based Approach to Proteomics and Chemical Proteomics / 2.Similarities in Protein Binding Sites / 3.Survey of Spectral Techniques Used to Study Proteins / Mass Spectral Studies of Proteome and Subproteome Mixtures. 4.Capillary Electrophoresis-Mass Spectrometry for Characterization of Peptides and Proteins / 5.Protein and Peptide Analysis by Matrix-Assisted Laser Desorption/Ionization Tandem Mass Spectrometry (MALDI MS/MS) / 6.Characterization of Glycosylated Proteins by Mass Spectrometry Using Microcolumns and Enzymatic Digestion / 7.Surface-Enhanced Laser Desorption/Ionization Protein Biochip Technology for Proteomics Research and Assay Development / 8.An Approach to the Reproducibility of SELDI Profiling / Part 2. Protein-Protein (or Peptide) Interactions: Studies in Parallel and with Mixtures. 9.Mass Spectrometric Applications in Immunoproteomics / 10.Near-Infrared Fluorescence Detection of Antigen-Antibody Interactions on Microarrays / 11.Application of Shotgun Proteomics to Transcriptional Regulatory Pathways / 12.Electrophoretic NMR of Protein Mixtures and its Proteomic Applications / Part 3. Chemical Proteomics: Studies of Protein-Ligand Interactions in Pools and Pathways. 13.Characterizing Proteins and Proteomes Using Isotope-Coded Mass Spectrometry / 14.Surface Plasmon Resonance Biosensors' Contributions to Proteome Mapping / 15.Application of In-Cell NMR Spectroscopy to Investigation of Protein Behavior and Ligand-Protein Interaction inside Living Cells / 16.An Overview of Metabonomics Techniques and Applications / Structural Proteomics: Parallel Studies of Proteins. 17.NMR-Based Structural Proteomics / 18.Leveraging X-Ray Structural Information in Gene Family-Based Drug Discovery: Application to Protein Kinases / 19.EPR Spectroscopy in Genome-Wide Expression Studies /
Summary of Chapters and Future Prospects for Spectral Techniques in Proteomics, Summarized by D.S. Sem (from each contributor)
・Covers new approaches in structural proteomics, metabolomics, and structure-based drug design ・Includes an overview of structural proteomics and chemical proteomics
・Presents widely used methods such as MALDI, SELDI, ICAT, tandem MS, and shotgun proteomics
・Covers spectroscopic tools including ESI, SPR, EPR, NIR fluorescence, x-ray crystallography and NMR *
496-17 登録日 07.09.02
