Takahashi, N. et al.
Proteomic Biology Using LC/MS
Large Scale Analysis of Cellular Dynamics and Function
LC/MSを利用したプロテオミクス生物学
John Wiley & Sons 2007.12
254 pp.(H)
ISBN 0-471-66258-5
9,200円
Contents
Chapter 1. Overview of Proteomics. What is the proteomics?: 1-2 Proteomic analysis using two-dimensional gel electrophoresis (2DE) and mass spectrometry / 1-3 Strategies for characterizing an entire proteome and understanding the proteome function/ Chapter 2. Proteomic Tools for Analysis of Cellular Dynamics: 2-1 LC-BASED PROTEOMICS TECHNOLOGIES/ 2-2 Development of quantitative proteomics/ Chapter 3. Dynamics of Functional Cellular Machinery: From Statics to Dynamics in Proteomic Biology. From statics to dynamics in proteomic biology: 3-1 DYNAMIC ANALYSIS OF CELLULAR FUNCTION/ 3-2 Dynamics of Ribosome Biogenesis / 3-3 Dynamic analyses of Sub-cellular structures/
＊This is one of the first books to focus on the dynamic aspect of proteomes. The book introduces proteomics to the newcomer, reviews the theoretical aspects of proteomics and its state-of-the art technologies, along with a number of biological applications using "classical" proteomic technology. The book also presents a new concept, the Dynamome, or the expression of a comprehensive molecular set that participates in the whole dynamic process of a series of cellular events. *
Watson, J. T. & Sparkman , O. D. ed.
Introduction to Mass Spectrometry 4th ed.
insrumentation, applications, and strategies for data interpretation
（質量分析入門第４版）
John Wiley & Sons 2007.12
862 pp.(H)
ISBN 0-470-51634-8
16,200円
Contents
1. Introduction/ 2. The Mass Spectrometer/ 3. Mass Spectrometry/Mass Spectrometry/ 4. Inlet Systems/ 5. Strategies for Data Interpretation (Other than Fragmentation)/ 6. Electron Ionization/ 7. Chemical Ionization/ 8. Electrospray Ionization/ 9. MALDI/ 10. GC/MS/ 11. Liquid Chromatography/Mass Spectrometry/ 12. Analysis of Proteins and other Biopolymers/ Index/
* Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references. *
Zachariou, M. ed.
Affinity Chromatography 2nd ed.
Methods and Protocols
Springer-Verlag 2008.
348 pp.(H)
ISBN 1-58829-659-8
13,200円
Contents
Part.1:PROPOSED TABLE OF CONTENTS: 1. Affinity Chromatography: History, Perspectives, Limitations and Prospects / Part.2:VARIOUS MODES OF AFFINITY CHROMATOGRAPHY: 2. Immobilized Metal Ion Affinity Chromatography of Native Proteins/ 3. Affinity Precipitation of Proteins Using Metal Chelates / 4. Immunoaffinity Chromatography/ 5. Dye-ligand Chromatography / 6. Purification of Proteins Using Displacement Chromatography/ Part.3:AFFINITY CHROMATOGRAPHY USING PURIFICATION TAGS: 7. Rationally Designed Ligands for use in Affinity Chromatography: an Artificial Protein L / 8. Phage display of Peptides in Ligand Selection for use in Affinity Chromatography / 9. Preparation, Analysis and Use of an Affinity Adsorbent for the Purification of GST Fusion Protein / 10. Immobilized Metal Ion Affinity Chromatography of Histidine-tagged fusion proteins / 11. Methods for the Purification of HQ-Tagged Proteins/ 12. Amylose Affinity Chromatography of Maltose-Binding Protein: Purification by both Native and Novel Matrix-Assisted Dialysis-Refolding Methods/13. Methods for the Detection of Protein-Protein and Protein-DNA Interactions using Halo-Tag TM/ 14. Site-specific Cleavage of Fusion Proteins / 15. The Use of TAGzyme for the efficient Removal of N-terminal His-tags/ Part.4:VARIOUS APPLICATIONS OF AFFINITY CHROMATOGRAPHY: 16. Affinity Processing of Cell-containing Feeds Using Monolithic Macroporous Hydrogels, Cryogels/ 17. Monolithic Bioreactors for Macromolecules/ 18. Plasmid DNA Purification via the Use of a Dual Affinity Protein/ 19. Affinity Chromatography of Phosphorylated Proteins/ 20. Protein Separation Using Phospholipid Chromatography)/ 21. Analysis of Proteins in Solution Using Affinity Capillary Electrophoresis/ index/ *
Villas-Boas, S. G. et al.
Metabolome Analysis
An Introduction
John Wiley & Sons 2007.2
311 pp.(H)
ISBN 0-471-74344-5
9,700円
Contents
PREFACE / LIST OF CONTRIBUTORS / PART I: CONCEPTS AND METHODOLOGY. 1 Metabolomics in Functional Genomics and Systems Biology / 2 The Chemical Challenge of the Metabolome / 3 Sampling and Sample Preparation / 4 Analytical Tools / 5 Data Analysis / PART II: CASE STUDIES AND REVIEWS. 6 Yeast Metabolomics: The Discovery of New Metabolic Pathways in Saccharomyces cerevisiae / 7 Microbial Metabolomics: Rapid Sampling Techniques to Investigate Intracellular Metabolite Dynamics―An Overview / 8 Plant Metabolomics / 9 Mass Profi ling of Fungal Extract from Penicillium Species / 10 Metabolomics in Humans and Other Mammals. INDEX. *
Funk, W. et al.
Quality Assurance in Analytical Chemistry 2nd ed.
Applications in Environmental, Food and Materials Analysis, Biotechnology, and Medical Engineering
Wiley-VCH 2007.1
277 pp. (H)
ISBN 3-527-31114-9
15,700円
Contents
Preface / List of Symbols / Introduction. 1 General Differentiation of Analytical Processes / 2 Quality of Analytical Processes and Results / 3 The System of Analytical Quality Assurance / 4 The Four-Phase Model of Analytical Quality Assurance / Part 1 Phase I: Establishing a New Analytical Procedure. 1 Introduction / 2 Calibration of the Fundamental Analytical Procedure / 3 Analyses at Very Low Concentrations / 4 Validation of Individual Process Steps and Examination of Matrix Influences / 5 Additional Statistical Methods / 6 Use of Internal Standards / 7 Preparing for Routine Analysis / 8 Summary of the Results of Phase I (Process Development): Documentation / Part 2 Phase II: An Analytical Process Becomes Routine; Preparative Quality Assurance. 1 Introduction / 2 Selection of the Analytical Procedure / 3 The “Training” Phase of the Process / 4 Establishment of Quality Objectives to be Adhered to in Routine Usage / 5 Control Samples for Internal Quality Assurance / 6 The Control Chart System / Part 3 Phase III: Routine Quality Assurance. 1 Introduction / 2 Fundamental Measures of Internal Quality Assurance / 3 Routine Quality Control / 4 Special Quality Problems in Routine Analysis / 5 Corrective Measures / 6 Documentation and Archiving / Part 4 Phase IV: External Analytical Quality Assurance. 1 Introduction / 2 Audits / 3 Interlaboratory (or Round Robin) Tests / 4 Effects of Internal Quality Assurance on the Results of Interlaboratory Tests / 5 Conclusion / Part 5 Definitions. 1 Quality and Quality Management / 2 Analytical Terms / 3 Analytical Results / 4 Deviation, Uncertainty / 5 Materials, Samples / 6 Statistical Tests / 6 References. Appendix / Subject Index. *
Subramanian, G. ed.
Bioseparation and Bioprocessing 2nd ed.(2 Volume Set)
生体分離と生体処理
Wiley-VCH 2007.11
798 pp (H) *2 Volume Set
ISBN 3-527-31585-3
67,000円
Contents
VOLUME 1: Part 1. STRATEGY AND DEVELOPMENT: 1.Process Development: when to start, when to stop/ 2.Strategies in downstream processing/ Part 2. BIOPROCESS AND EARLY DSP: 3.Process Development and Optimization for Biotechnology Production ? Monoclonal Antibodies/ 4.Dynamics of cellular response to recombinant protein overexpression in Esscherichia coli/ Part 3. PREPARATIVE (CHROMATOGRAPHIC) METHODS: 5.Ion Exchange Chromatography in Biopharmaceutical Manufacturing/ 6.Displacement chromatography of biomacromolecules/ 7.The Purification of Biomolecules by Countercurrent Chromatography/ 8.Continuous chromatography in the down-stream processing of compounds from biotechnological and natural origin/ 9.Continuous Annular Chromatography/ 10.Principles of membrane separation processes/ 11.Affinity Precipitation/
VOLUME 2: Part 4. SPECIFIC BIOPROCESSES AND SEPARATION METHODS: 12.Biological fuel cells/ 13.Removal and Analysis of Contaminants and Impurities/ 14.High throughput RNAi: Emerging technology for functional Genomics/ 15.Developing an Antibody Purification Process ? / 16.The Many Ways to Purify Plasmis DNA ? Choosing the right purification strategy based on the downstream application/ 17.Advanced Fractionation methods and analysis for proteomics applications/ Part 5. SAFETY, QUALITY CONTROL, VALIDATION AND REGUATORY CONSIDERATIONS: 18.Biosafety/ 19.The Manufacture of Gene Therapy Products and Viral Vaccines/ 20.The Virus and Prion safety of Biopharmaceuticals/ 21.Protein Glycosylation: Analysis and Characterization/ 22.High Throughput glycoanalysis for use in Bioprocessing/ 23.Quality Control of Impantable Drug Delivery Systems? / Part 6. ANALYTICAL METHODS AND TECHNOLOGIES: 24.Polymerase Chain Reaction: an Analytical Tool in Bioprocessing/ 25.Electrokinetic Separations/ 26.Capillary Isoelectric Focusing Methods for Charge-Based Analysis of Biopharmaceuticals/
＊In this new edition of the only resource to systematically cover all post-production issues, over 70 % of the content is new or rewritten in line with the rapidly evolving technology in the field. By combining the experience of academic experts, managers from the pharmaceutical and biotech industry, as well as independent consultants, biological product recovery is viewed from every possible angle, including biosafety and regulatory issues. *
Kowalska, T. & Sherma, J. ed.
Thin Layer Chromatography in Chiral Separations and Analysis
CRC Press 2007.7
436 pp. (H)
ISBN 0-8493-4369-0
24,800円
Contents
1.Introduction. 2.Chirality. 3.Commercial Stationary Phases for Enantioseparations. 4.Planar Chromatographic Enantioseparations on Non-commercial CSPs. 5.Planar Chromatographic Enantioseparations on Non-Commercial CCPs. 6.Chiral Modifiers of Mobile Phases. 7.An Overview of the Chiral Separation Mechanisms. 8.Separation of Diastereoisomers by means of TLC. 9.Selected Bottlenecks of Densitometric Detection with Chiral Analytes. 10.Chirality of Pharmaceutical Product Racemates. 11.Chiral Separation of the Selected ﾟ-blockers. 12.Chiral Separation of Aminoacid Enantiomers. 13.Chiral Separation of NSAIDs. 14.Determination of Components in Selected Drug Racemates. 15.Chiral Separations using Marfey's Reagent/ *
* Investigation and control of chirality, which is executed almost exclusively using chromatographic techniques, ranks among the most difficult separation tasks. As the first book devoted to this topic, Thin Layer Chromatography in Chiral Separations and Analysis presents updated information on this important field. The first part of this book discusses the problem of chirality in general and the technical possibilities of carrying out enantiomer separations in detail. Addressing significant application areas, the second part of the text provides a comprehensive overview of enantioseparations and densitometric analyses that have been successfully achieved using thin layer chromatography. *
McMahon , G.
Analytical Instrumentation
A Guide to Laboratory, Portable and Miniaturized Instruments
（分析機器）
John Wiley & Sons 2008.1
318 pp.(H)
ISBN 0-470-02795-9
12,000円
Contents
Section I: Introduction/ Section II: Laboratory Analytical Instrumentation: 1. Spectrometric instruments/ 2. Separation instruments/ 3. Imaging instruments/ 4. Electrochemical instruments/ 5. Other instruments/ Section III: Portable Analytical Instrumentation: 6. Portable instruments in the laboratory/ 7. Portable instruments in various applications/ Section IV: Process Analytical Instrumentation: 8. Process analytical instrumentation in industry/ Section V: Miniaturised Analytical Instrumentation: 9. Chip-based instrumentation/ Index/
* This valuable resource covers the principles of analytical instrumentation used by today's chemists and biologists and presents important advances in instrumentation, such as the drive to miniaturise and lab-on-a-chip devices. In terms of the lab-based analytical instrumentation, the five main categories of techniqueﾑspectroscopic, chromatographic, electrochemical, imaging and thermoanalytical, are included and presented in a practical, not theoretical way. *
545-20 登録日 08.03.22
