Cooper, C. & Woolf, A.
Osteoporosis
Elsevier Science Ltd. 2006.9
200 pp. (P)
ISBN 0-08-044685-X
14,000円
Contents
1.Epidemiology of osteoporosis / 2.Fractures in the elderly: epidemiology and demography / 3.Pathogenesis of osteoporosis / 4.Prenatal and childhood influences on osteoporosis / 5.Corticosteroid osteoporosis / 6.Lower peak bone mass and its decline / 7.The role of bone turnover markers and risk factors in the assessment of osteoporosis and fracture risk / 8.The use of bone densitometry in clinical practice / 9.Role of biochemical markers in the management of osteoporosis / 10.Glucocorticoid-induced osteoporosis / 11.Osteoporosis in men / 12.Osteoporosis in childhood diseases: prevention and therapy / 13.Post-menopausal osteoporosis / 14.How to prevent fractures in the individual with osteoporosis / 15.Non-pharmacological interventions / 16.Phyto-oestrogens / Oestrogen and selective receptor modulators /(SERMS): current roles in the prevention and treatment of osteoporosis/ 17. Role of bisphosphonates and calcitonin in the prevention and treatment of osteoporosis / 18.Biologic therapies in osteoporosis / 19.Anabolic bone binding treatment [PTH] analogues and strontium / 20.Cost utility of treatment of osteoporosis / 21.Risk assessment in osteoporosis / 22.Future methods in the assessment of bone mass and structure / **
* This prestigious text offers the most up-to-date advice on the identification and management of osteoporosis. Derived from the highly acclaimed journals Best Practice and Research - Clinical Endocrinology & Metabolism and Best Practice and Research - Rheumatology this fully updated volume provides a logical progression through definition, diagnosis, epidemiology, as well as the latest advice on disease prevention, treatment and screening. Fully illustrated throughout, the book draws upon the expertise of some of the world's leading experts in the field, providing a publication that gives a truly international perspective to the management of osteoporosis. *
Krebs, J. ed.
Calcium : A Matter of Life or Death
Elsevier Science Ltd. 2007.8
584 pp. (H)
ISBN 0-444-52805-9
26,000円
Contents
Part 1.History and Evolution of Calcium Biochemistry/ Part 2.Structural and Functional Aspects of Calcium-Binding Proteins/ Part 3.Calcium Homeostasis of Cells and Organelles/ Part 4.Modulation of Calcium Functions/ Part 5.Ca2+ signaling, a spatio-temporal phenomenon/ *
Bronner, F. et al.
Engineering of Functional Skeletal Tissues
Springer-Verlag 2007.
178 pp. (H)
ISBN 1-85233-962-4
29,800円
Contents
Preface / Contributors / 1 Stem Cells and the Art of Mesenchymal Maintenance / 2 Osteogenic Growth Factors and Cytokines and Their Role in Bone Repair / 3 Bone Allograft Safety and Performance / 4 Biodegradable Orthopedic Implants / 5 Titanium Fiber Mesh: A Nondegradable Scaffold Material / 6 Engineering Polymeric Scaffolds for Bone Grafts / 7 Injectable Scaffolds for Bone and Cartilage Regeneration / 8 Motion and Bone Regeneration / 9 Dental Applications of Bone Biology / 10 Multiscale Computational Engineering of Bones: State-of-the-Art Insights for the Future / Index.
* This is the 3rd in a series of reviews, centered on a single major topic of bone replacement (Vol. 1 Bone Formation, Vol. 2 Bone Resorption) written by acknowledged authorities in the field. The biology of stem cells and cell signals, knowledge needed to make stem cell engineered, bone tissue a reality and how to prevent bone allograft infection is discussed. Furthermore, non-degradable and biodegradable scaffolds, necessary implants to attract bone cells and build suitable bone replacements follow. Other topics are motion and bone degeneration analysis and effect of mechanical factors on bone healing, implants and their role in reparative dentistry and the application of computational modeling to prosthesis design. *
Curry, J. D.
Bones : Structure and Mechanics
Princeton University Press 2006.
456 pp.(P)
ISBN 0-691-12804-9
6,800円
Contents
1.The Structure of Bone Tissue/ 2.The Mechanical Properties of Materials/ 3.The Mechanical Properties of Bone/ 4.The Adaptation of Mechanical Properties to Different Functions/ 5.Cancellous Bone/ 6.The Properties of Allied Tissues/ 7.The Shapes of Bones/ 8.Articulations / 9.Bones, Tendons, and Muscles/ 10.Safety Factors and Scaling Effects in Bones/ 11.Modeling and Reconstruction/ 12.Summing up/ References/ Index/ *
Stoltz, J.-F. ed.
Mechanobiology: Cartilage and Chondrocyte - Vol. 4
Biomedical and Health Research Vol. 68
IOS Press 2006.9
452 pp. (H)
ISBN 1-58603-648-3
21,100円
Contents
* Over recent years, there has been increasing interest in the fundamental role played by local mechanical parameters in chondrocyte regulation and cartilage dysfunction as a first step in the development of osteoarthritis. This is how the idea of mechanobiology and the concept of mechanotransduction were born in the 90's. Indeed, a broad diversity of physiological phenomena is induced by mechanical stimuli (hearing, orientation to gravity, touch, tissue remodelling...) but the mechanism by which mechanical forces may regulate a physiological response is still unknown. In other respects, the concept of regenerative medicine has recently developed in parallel to this. Regenerative medicine is an emerging multidisciplinary field involving medicine, biology, chemistry, mechanics and engineering that is likely to revolutionize the ways we improve the health and quality of life by restoring, maintaining or enhancing tissue and organ functions. Indeed, human tissues do not regenerate spontaneously and healing is only a stopgap that may be associated with contraction which in turn may prevent regeneration. Tissue engineering through the in vitro preparation of biotissues presents an interesting alternative. Today, the in vitro preparation of biological tissues such as cartilage, bone, tendon, vessel, heart muscle, skin, brings out major expectations for the next decade. However, to each type of tissue correspond a large number of potential methods related to the support, the cells used (tissular cells or stem cells) and to the conditions of the environment (culture medium and mechanical forces). The aim of this publication is to provide a thoughtful and balanced dissertation on new crucial concepts with clinical implications. *
Pearson, D. & Miller, C. G. ed.
Clinical Trials in Osteoporosis 2nd ed.
Springer-Verlag 2007.
292 pp. (P)
ISBN 1-84628-389-2
13,000円
Contents
Introduction.- Part I. Study Design and the Pre-trial Phase: Study Design and Endpoints.- Ethical Considerations.- Standardization and Pre-trial Quality Control.- Part II. Performing the Trial: Organization of the Clinical Trial by the Sponsor.- Local Site Organization.- Clinical Trial Quality Assurance.- Laboratory and Instrument Quality Control.- Part III. Data Analysis and Presentation: Data Analysis and Presentation: Writing a Paper for Publication.- Part IV. Background: Current Therapies for Osteoporosis.- The Ideal Drug for the Treatment of Osteoporosis.- Instrument Measurements in Osteoporosis Clinical Trials: Evaluating the Endpoints.- Biochemical Markers of Bone Turnover.- Future Therapies and Clinical Trials.- Appendix A: Glossary.- Appendix B: Sample Study Data. **
* This second revised and updated edition is a practical handbook on clinical trials in the growing field of osteoporosis. Topics covered include study design, technical issues, data collection, quality assurance, data analysis, and presentation. Clinical Trials in Osteoporosis takes the user through the process step-by-step from start to finish. It also provides a background on regulatory guidelines, ethical implications, endpoints, current therapies, and the ideal drug to use. It will serve as a practical manual for clinicians and scientists new to the subject and provide a standard for existing centers to measure themselves against. *
Williams, R. J. ed.
Cartilage Repair Strategies
Humana Press 2007.5
374 pp. (H)
ISBN 1-58829-629-6
31,000円
Contents
1 Articular Cartilage: Structure, Biology and Function/ 2 Evaluating Outcome Following Cartilage Procedures/ 3 MRI and Articular Cartilage: Evaluating Lesions and Post-Repair Tissue/ 4 Decision Making in Cartilage Repair Procedures/ 5 Non-operative Treatment Options for Symptomatic Cartilage Lesions/ 6 Marrow Stimulation and Microfracture/ 7 Cartilage Repair Using an Injectable Chitosan-based Cell Delivery Method/ 8 Autologous Osteochondral Transplantation/ 9 Articular Cartilage Resurfacing Using Synthetic Resorbable Scaffolds/ 10 Articular Cartilage Resurfacing Using Autologous Chondrocyte Implantation/ 11 Matrix Associated Cartilage Implantation (MACI)/ 12 Cell Based Cartilage Repair Using the Hyalograft Transplant/ 13 Cell Based Cartilage Repair Using Alginate Beads/ 14 Osteochondral Allograft Transplantation/ 15 The Role of Osteotomy in the Setting of Articular Cartilage Repair/ 16 Management of Osteochondritis Dissecans/ 17 Meniscus Transplantation and Cartilage Resurfacing: Considerations, Indications, and Approach/ 18 Chondral Repair Strategies in the Ankle Joint/ 19 Chondral Repair Strategies in the Hip Joint / 20 Rehabilitation Strategies Following Articular Cartilage Surgery/ *
612-13 登録日 07.08.21
