Dopico, A. ed.
Methods in Membrane Lipids
methods in molecular biology
Humana Press 2007.6
775 pp. (H)
ISBN 1-58829-662-8
22,500円
Contents
1 A glance at the structural and functional diversity of membrane lipids/ 2 Membrane lipid polymorphism: relationship to bilayer properties and protein function/ 3 Acrylodan-labeled intestinal fatty acid binding protein to measure concentrations of unbound fatty acids/ 4 Measuring molecular order and orientation using Coherent-anti Stokes/ 5 Preparation of oriented, fully hydrated lipid samples for structure determination using X-ray scattering/ 6 Nuclear Magnetic Resonance investigation of oriented lipid membranes/ 7 Molecular dynamics simulations as a complement to Nuclear Magnetic Resonance and X-ray diffraction measurements/ 8 Use of inverse theory algorithms in the analysis of biomembrane Nuclear Magnetic Resonance data/ 9 Statistical thermodynamics via computer simulation to characterize phospholipid interactions in membranes/ 10 Fluorometric assay for detection of sterol oxidation in liposomal membranes/ 11 Fluorescence detection of signs of sterol superlattice formation in lipid membranes/ 12 Differential scanning calorimetry in the study of lipid phase transitions in model and biological membranes: practical considerations/ 13 Pressure-perturbation calorimetry/ 14 Fourier transform infrared spectroscopy in the study of lipid phase transitions in model and biological membranes: practical considerations/ 15 Optical dynamometry to study phase transitions in lipid membranes/ 16 Fluorescence assays for measuring fatty acid binding and transport through membranes/ 17 Measurement of lateral diffusion rates in membranes by Pulsed Magnetic Field Gradient, Magic Angle-Spinning Proton Nuclear Magnetic Resonance/ 18 Using Fluorescence Recovery After Photobleaching to measure diffusion in membranes/ 19 Single molecule fluorescence microscopy to determine phospholipid lateral diffusion/ 20 Modeling two- and three-dimensional diffusion/ 21 Measurement of water and solute permeability by stopped-flow fluorimetry/ 22 Fluorescence microscopy to study pressure between lipids in giant unilamelar vesicles/ 23 X-ray scattering and solid-state deuterium Nuclear Magnetic Resonance probes of structural fluctuations in lipid membranes/ 24 Determination of lipid spontaneous curvature from X-ray examinations of inverted hexagonal phases/ 25 Shape analysis of giant vesicles with fluid phase coexistence by laser scanning microscopy to determine curvature, bending elasticity and line tension/ 26 Laser tweezer deformation of giant unilamellar vesicles/ 27 Measurement of lipid forces by X-ray diffraction and osmotic stress/ 28 Micropipette aspiration for measuring elastic properties of lipid bilayers/ 29 Langmuir films to determine lateral surface pressure on lipid segregation/ 30 Detergent and detergent-free methods to define lipid rafts and caveolae/ 31 Near field scanning optical microscopy to identify membrane microdomains/ 32 Fluorescence microscopy to study domains in supported lipid bilayers/ 33 Fluorescence resonance energy transfer to characterize cholesterol-induced domains/ 34 Lipid domains in supported lipid bilayers for atomic force microscopy/ 35 Nuclear Magnetic Resonance structural studies of membrane proteins in micelles and bilayers/ 36 Laurdan studies of membrane lipid-acetylcholine receptor protein interactions/ 37 Single-molecule methods for monitoring changes in bilayer elastic properties/ 38 Ion channel reconstitution/ 39 The use of differential scanning calorimetry to study drug-membrane interactions/ 40 Atomic force microscopy to study interacting forces in phospholipid bilayers containing general anesthetics/
* This book presents a compendium of methodologies for the study of membrane lipids, varying from traditional lab bench experimentation to computer simulation and theoretical models. This volume provides a comprehensive set of techniques for studying membrane lipids, and their interactions with other membrane lipids, with membrane proteins, and with exogenous agents such as anesthetics. *
Hamill, O. et al.
Mechanosensitive Ion Channels Part A
Current Topics in Membranes Vol. 58
Academic Press 2007.4
448 pp. (H)
ISBN 0-12-153358-1
28,000円
Contents
1: The Mechanical Properties of Bilayers / 2: Molecular Dynamic Modeling of MS Channels / 3: Structures of the Prokaryotic Mechanosensitive Channels MscL and MscS / 4: 3.5 Billion Years of Mechanosensory Transduction: Structure and Function of Mechanosensitive Channels in Prokaryotes / 5: Activation of Mechanosensitive Ion Channels by Forces Transmitted through Integrins and the Cytoskeleton / 6: Thermodynamics of Mechanosensitivity / 7: Flexoelectricity and Mechanotransduction / 8: Lipid Effects on Mechanosensitive Channels / 9: Functional Interactions of the Extracellular Matrix with Mechanosensitive Channels / 10: MSCL: The Bacterial Mechanosensitive Channel of Large Conductance / 11: The Bacterial Mechanosensitive Channel MscS: Emerging Principles of Gating and Modulation / 12: Structure function relations of MscS / 13: The MscS Cytoplasmic Domain and its Conformational Changes upon the Channel Gating / 14: Microbial TRP Channels and Their Mechanosensitivity / 15: MSCS-Like Proteins in Plants / 16: Delivering Force and Amplifying Signals in Plant Mechanosensing / 17: MS Channels in Tip Growing Systems / *
Hamill, O. et al.
Mechanosensitive Ion Channels Part B
Current Topics in Membranes Vol. 59
Academic Press 2007.4
616 pp.(H)
ISBN 0-12-153359-X
23,000円
Contents
1.ENaC Proteins in Vascular Smooth Muscle Mechanotransduction/ 2.Regulation of the Mechano-Gated K2P Channel TREK-1 by Membrane Phospholipids/ 3.MechanoTRPs and TRPA1/ 4.TRPC/ 5.The Cytoskeletal Connection to Ion Channels as a Potential Mechanosensory/ 6.Mechanism. Lessons From Polycystin-2 (TRPP2)/ 7.Lipid Stress at Play: Mechanosensitivity of Voltage-Gated Channels/ 8.Hair Cell Mechanotransduction: The Dynamic Interplay between Structure and Function/ 9.Pharmacology of Hair Cell MS Channels/ 10.Hair Cell Mechanotransduction/ 11.Models of Hair Cell Mechanotrasduction/ 12.Touch/ 13.Mechanosensitive Ion Channels in Dystrophic Muscle/ 14.Mechanotransduction in Endothelial Cells/ 15.MS Channels in Tumor Cell Migration/ 16.Mechanosensitive Channels in Regulating Smooth Muscle Contraction in the GI/ 17.Mechanosensitive Ion Channels in Blood-Pressure-Sensing Baroreceptor Neurons/ *
Langel, U.
Cell-Penetrating Peptides: Processes and Applications
細胞透過性ペプチド
CRC Press 2006.8
624 pp.(H)
ISBN 0-8493-5090-5
28,500円
Contents
1.Classes of Cell-Penetrating Peptides. 2.Mechanisms of Cell Penetration, Interactions of Cell-Penetrating Peptides with Plasma Membranes and Lipid Models. 3.Applications of Cell-Penetrating Peptides/ * This book fills the need for a comprehensive update of the research concerning those specialized cell-penetrating peptides (CPPs) to which drug molecules can attach and pass through the cell membrane. *
Hirabayashi, Y. et al.
Sphingolipid Biology
Springer-Verlag (Tokyo) 2006.
531 pp.(H)
ISBN 4-431-34198-6
19,000円
Contents
Part 1.Overview/ Part 2.Biosynthesis,Transport of Sphingolipids/ Part 3.Generation and Degradation of Sphingolipid Signaling Molecules/ Part 4.Membrance Domain and Biological Function/ Part 5.Membrance Lipid Domain and Human Pathobiology/ Part 6.S1P Signaling and SIPR/ Part 7.Advanced Technology in Sphingolipid Biology/ Appendix/ Keyword Index/ *
Wikstrom, M. ed.
Biophysical and Structural Aspects of Bioenergetics
バイオエナジェテックスの生物物理
Royal Society of Chemistry 2005.12
396 pp.(P)
ISBN 0-85404-346-2
20,200円
Contents
* 本書は、この分野を開拓し発展させてきた国際的に著名なエキスパートたちの寄稿を集めて編集したもので、ごく最近の重要な進歩を記述したスナップショットです。結果的に研究の現状の包括的な概観を提供しています。
1.Principles of Molecular Bioenergetics and the Proton Pump of Cytochrome Oxidase/ 2.Proton Entry, Exit and Pathways iin Cytochrome Oxidase: Insight from 'Conserved' Water/ 3.Structural Chemical Studies on the Reaction Mechanism of Cytochrome c Oxidase/ 4.Mechanisms of Redox-Coupled Proton Pumping by Respiratory Oxidases/ 5.Quantum Chemical Models of O2 Bond Cleavage and Proton Pumping in Cytochrome Oxidase/ 6.The bc1 Complex: What is there Left to Argue About?/ 7.Insights into the Mechanism of Mitochondrial Complex I from its Distant Relatives, the [NiFe] Hydrogenases/ 8.Current Knowledge About the Mechanisms of Energy Transduction by Respiratory Complex I/ 9.Structure of Photosystem II from Thermosynechococcus Elongatus/ 10.A Structural View of Proton Transport by Bacteriohodopsin/ 11.The Dynamics of Proton Transfer Across Bacteriorhodopsin Explored by FT-IR Spectroscopy/ 12.Intraprotein Proton Transfer-Concepts and Realities from the Bacterial Photosynthetic Reaction Center/ 13.Infrared Protein Spectroscopy as a Tool to Study Protonation Reactions within Proteins/ 14.Inhibitors of Mitochondrial F1-ATPase/ 15.The Passion of the Permease/ 16.Hydride Transfer and Proton Translocation by Nicotinamide Nucleotide Transhydrogenase/ Subject Index/ *
635-10 登録日 07.07.31