Peinemann, K-V. & Nunes, S. P. ed.
Membrane Technology Vol.1
Membranes for Life Science
Wiley -VCH 2007.12
343 pp.(H)
ISBN 3-527-31480-6
25,600円
Contents
1.Introduction/ 2.Membranes for Haemodialysis/ 3.Gas Exchange Membranes for Artificial Lung and Lung Support Systems/ 4.Membranes for Blood Plasma Separation and Blood Plasma Treatment/ 5.Membranes in the Biopharmaceutical Industry/ 6.Membrane Applications in Red and White Biotechnology/ 7.Membranes in Controlled Release/ 8.Drug Delivery Through Skin -Overcoming the Ultimate Biological Membrane/ 9.Application of Membranes in Tissue Engineering and Biohybrid Organ Technology/ 10.Membranes in Bio-artificlal Pancreas/
* Examining artificial membranes in terms of biocompatibility, drug delivery and controlled release, this book illustrates how existing membrane technologies are being exploited and advanced in emerging medical applications. This work, edited by internationally recognized experts, has author contributions from prominent members of this field who discuss details of all aspects of this technology. This volume provides broad, yet detailed information on synthetic membranes and their applications, including dialysis and artificial kidneys, gas exchange, artificial lungs, devices to assist liver function, and membrane affinity chromatography. *
Saks, V. ed.
Molecular System Bioenergetics
Energy of Life
（分子システムと生体エネルギー）
Wiley -VCH 2007.11
633 pp. (H)
ISBN 3-527-31787-2
27,500円
Contents
Introduction/ Part 1.MOLECULAR SYSTEM BIOENERGETICS: BASIC PRINCIPLES, ORGANISATION AND DYNAMICS OF CELLULAR ENERGETICS: 1.Cellular Energy Metabolism and Integrated Oxidative Phosphorylation/ 2.Organization and Regulation of Mitochondrial Oxidative Phosphorylation/ 3.Integrated and Organized Cellular Energetic Systems: Theories of Cell Energetics, Compartmentation and Metabolic Channeling/ 4.On the Network Properties of Mitochondria/ 5.Structural Organization and Dynamics of Mitochondria in the Cells In Vivo/ Part 2.ENERGY TRANSFER NETWORKS, METABOLIC FEEDBACK REGULATION AND MODELING OF CELLULAR ENERGETICS: 6.Mitochondrial VDAC and its Complexes/ 7.Phospho-Creatine Circuit:/ 8.Integration of Adenylate Kinase, Glycolytic and Glycogenolytic Circuits in Cellular Energetics/ 9.Signaling by AMP-Activated Protein Kinase/ 10.Developmental and Functional Consequences of Disturbed Energetic Communication in Brain of Creatine Kinase Deficient Mice/ 11.System Analysis of Cardiac Energetics - Excitation-Contraction Coupling/ 12.Principles of Mathematical Modeling and In Silico Studies of Integrated Systems of Cellular Energetics/ 13.Modeling Energetics of Ion Transport, Membrane Sensing and System Biology of the Heart/ Part 3.APPLIED MOLECULAR SYSTEM BIOENERGETICS: 14.Mitochondrial Adaptation to Exercise and Training - A Physiological Approach/ 15.Mitochondrial Medicine: The Central Role of Cellular Energetic Depression and Mitochondria in Cell Pathophysiology/ 16.Tumour Cell Energetic Metabolome/ 17.AMPK and the Metabolic Syndrome/ 18.A Systems Biology Perspective of Obesity and Type 2 Diabetes/ *
Pebay-Peyroula, E. ed.
Biophysical Analysis of Membrane Proteins
Investigating Structure and Function
Wiley-VCH 2007.12
368 pp. (H)
ISBN 3-527-31677-9
24,400円
Contents
Introduction/ Part 1.STRUCTURAL APPROACHES: 1.Membrane Protein Structure Determination by Electron Cryo-microscopy/ 2.NMR Liquid or Solid State/ Part 2.MOLECULAR INTERACTION AND LARGE ASSEMBLIES: 3.,Analytical Ultracentrifugation: Membrane Protein Assemblies in the Presence of Detergent/ 4.SPR Biosensors for Characterizing Membrane-associated Proteins/ 5.Atomic Force Microscopy (AFM): High Resolution Imaging of Structure and Assembly of Membrane Proteins/ Part 3.DYNAMICS: 6.Molecular Dynamics Simulations/ 7.Understanding Structure and Function of Membrane Proteins Using Free Energy Calculations/ 8.Neutron Scattering to Study Membrane Structure and Dynamics/ Part 4.SPECTROSCOPIES: 9.Circular Dichroism: Folding and Conformational Changes of Membrane Proteins/ 10.Membrane Protein Structure and Conformational Change Probed Using Fourier Transform Infrared Spectroscopy/ 11.Raman Spectroscopy on Light Harvesting Complex/ Part 5.EXPLORING STRUCTURE-FUNCTION RELATIONSHIPS IN WHOLE CELLS: 12.Energy Transfer Technologies to Monitor the Dynamics and Signaling Properties of G-protein Coupled Receptors in Living Cells/ 13.Transport Characterization by Current Measurements/ *
* Meeting the need for a book on developing and using new methods to investigate membrane proteins, this is the first of its kind to present the full range of novel techniques in one resource. Top researchers from around the world focus on the physical principles exploited in the different techniques, and provide examples of how these can bring about important new insights. Following an introduction, further sections discuss structural approaches, molecular interaction and large assemblies, dynamics and spectroscopies, finishing off with an exploration of structure-function relationships in whole cells. *
Martin, D. ed.
Nanobiotechnology of Biomimetic Membranes
Fundamental Biomedical Technologies , Vol.1
Springer-Verlag 2007.1
174 pp. (H)
ISBN 0-387-37738-7
16,700円
Contents
1.The Significance of Biomimetic Membrane Nanobiotechnologyto Biomedical Applications/ 2.Langmuir-Blodgett Technique for Synthesis of Biomimetic Lipid Membranes / 3.Liposome Techniques for Synthesis of Biomimetic/ 4.Characterization and Analysis of Biomimetic Membranes/ 5.Biomimetic Membranes in Biosensor Applications / .About the Contributors / Index/
* Nanobiotechnology of Biomimetic Membranes describes the current state of research and development in biomimetic membranes for nanobiotechnology applications. The application areas in nanobiotechnology range from novel nanosensors, to novel methods for sorting and delivering bio-active moleculres, to novel drug-delivery systems. The success of these applications relies on a good understanding of the interaction and incorporation of macromoleculres in membranes and the funamental properties of the membrane itself. *
Subramanian, G. ed.
Bioseparation and Bioprocessing 2nd ed.(2 Volume Set)
生体分離と生体処理
Wiley-VCH 2007.11
798 pp (H) *2 Volume Set
ISBN 3-527-31585-3
67,000円
Contents
VOLUME 1: Part 1. STRATEGY AND DEVELOPMENT:
1.Process Development: when to start, when to stop/ 2.Strategies in downstream processing/ Part 2. BIOPROCESS AND EARLY DSP: 3.Process Development and Optimization for Biotechnology Production ? Monoclonal Antibodies/ 4.Dynamics of cellular response to recombinant protein overexpression in Esscherichia coli/ Part 3. PREPARATIVE (CHROMATOGRAPHIC) METHODS: 5.Ion Exchange Chromatography in Biopharmaceutical Manufacturing/ 6.Displacement chromatography of biomacromolecules/ 7.The Purification of Biomolecules by Countercurrent Chromatography/ 8.Continuous chromatography in the down-stream processing of compounds from biotechnological and natural origin/ 9.Continuous Annular Chromatography/ 10.Principles of membrane separation processes/ 11.Affinity Precipitation/
VOLUME 2: Part 4. SPECIFIC BIOPROCESSES AND SEPARATION METHODS:
12.Biological fuel cells/ 13.Removal and Analysis of Contaminants and Impurities/ 14.High throughput RNAi: Emerging technology for functional Genomics/ 15.Developing an Antibody Purification Process ? / 16.The Many Ways to Purify Plasmis DNA ? Choosing the right purification strategy based on the downstream application/ 17.Advanced Fractionation methods and analysis for proteomics applications/ Part 5. SAFETY, QUALITY CONTROL, VALIDATION AND REGUATORY CONSIDERATIONS: 18.Biosafety/ 19.The Manufacture of Gene Therapy Products and Viral Vaccines/ 20.The Virus and Prion safety of Biopharmaceuticals/ 21.Protein Glycosylation: Analysis and Characterization/ 22.High Throughput glycoanalysis for use in Bioprocessing/ 23.Quality Control of Impantable Drug Delivery Systems? / Part 6. ANALYTICAL METHODS AND TECHNOLOGIES: 24.Polymerase Chain Reaction: an Analytical Tool in Bioprocessing/ 25.Electrokinetic Separations/ 26.Capillary Isoelectric Focusing Methods for Charge-Based Analysis of Biopharmaceuticals/
＊In this new edition of the only resource to systematically cover all post-production issues, over 70 % of the content is new or rewritten in line with the rapidly evolving technology in the field. By combining the experience of academic experts, managers from the pharmaceutical and biotech industry, as well as independent consultants, biological product recovery is viewed from every possible angle, including biosafety and regulatory issues. *
Waigh, T.
Applied Biophysics
A Molecular Approach for Physical Scientists
応用生物物理学
John Wiley & Sons 2007.9
436 pp. (P)
ISBN 0-470-01718-X
8,200円
Contents
Preface / Acknowledgements / 1. The Building Blocks / 2. Mesoscopic Forces / 3. Phase Transitions / 4. Liquid Crystallinity / 5. Motility / 6. Aggregating Self-Assembly / 7. Surface Phenomena / 8. Biomacromolecules / 9. Charged Ions and Polymers / 10. Membranes / 11. Continuum Mechanics / 12. Biorheology / 13. Experimental Techniques / 14. Motors / 15. Structural Biomaterials / 16. Phase Behaviour of DNA / Appendix / Answers to Tutorial Questions / Index / *
* The topics covered in the book include: ・ Phase transitions that occur in biosystems (protein crystallisation, globule-coil transition etc) ・ Liquid crystallinity as an example of the delicate range of partially ordered phases found with biological molecules ・ How molecules move and propel themselves at the cellular level ・ The general features of self-assembly with examples from proteins ・ The phase behaviour of DNA *
635-11 登録日 08.02.17
