Rupp, B.
Biomolecular Crystallography
Principles, Practice, and Application to Structural Biology
（生体分子結晶学）

Garland Pub. 2009.10
800 pp.(H)
ISBN 0-8153-4081-8
　　　　　　　　　　　　　　　　　　　　　　　　　　　　12,500円

Contents
1.From Sequence to Crystals/ 2.Fundamentals of Protein Crystallography/ 3.From Crystals to Data/ 4.Determining Your Structure/ 5.Making Sense of Your Structure/ Index/

* Synthesizing over thirty years of advances into a comprehensive textbook, Biomolecular Crystallography describes the fundamentals, practices, and applications of protein crystallography. Deftly illustrated in full-color by the author, the text describes mathematical and physical concepts in accessible and accurate language. It distills key concepts for understanding the practice and analysis of protein crystal structures and contains examples of biologically-relevant molecules, complexes, and drug target structures. *

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Harris, R. K. et al. ed.
NMR Crystallography
NMR結晶学

John Wiley & Sons 2010.1
520 pp.(H)
ISBN 0-470-69961-2
　　　　　　　　　　　　　　　　　　　　　　　　　　　　15,900円

Contents
* The term "NMR Crystallography" has only recently come into common usage, and even now causes raised eyebrows within some parts of the diffraction community. The power of solid-state NMR to give crystallographic information has considerably increased since the CPMAS suite of techniques was introduced in 1976. In the first years of the 21st century, the ability of NMR to provide information to support and facilitate the analysis of single-crystal and powder diffraction patterns has become widely accepted.

* Indeed, NMR can now be used to refine diffraction results and, in favorable cases, to solve crystal structures with minimal (or even no) diffraction data. The increasing ability to relate chemical shifts (including the tensor components) to the crystallographic location of relevant atoms in the unit cell via computational methods has added significantly to the practice of NMR crystallography. Diffraction experts will increasingly welcome NMR as an allied technique in their structural analyses. Indeed, it may be that in the future crystal structures will be determined by simultaneously fitting diffraction patterns and NMR spectra.

* This Handbook is organised into six sections. The first contains an overview and some articles on fundamental NMR topics, followed by a section concentrating on chemical shifts, and one on coupling interactions. The fourth section contains articles describing how NMR results relate to fundamental crystallography concepts and to diffraction methods. The fifth section concerns specific aspects of structure, such as hydrogen bonding. Finally, four articles in the sixth section give applications of NMR crystallography to structural biology, organic & pharmaceutical chemistry, inorganic & materials chemistry, and geochemistry. *

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Hinterdorfer, P. & van Oijen, A. ed.
Handbook of Single-Molecule Biophysics
単一分子の生物物理ハンドブック

Springer-Verlag 2009.7
626 pp.(H)
ISBN 0-387-76496-8
　　　　　　　　　　　　　　　　　　　　　　　　　　　　31,400円

Contents
* この十年間で数多くの新しい生物物理実験法の進歩が見られました。本ハンドブックは、蛍光検出法、原子間力顕微鏡法、光と磁気トラッピング法を含む単一生物分子のモニターと操作を実施する実験技術を解説します。超解像度や機能的画像法における単一分子技法の利用法、折りたたみ、タンパク質やDNAの高分子物理学、酸素と生化学、生体膜中の単一分子、生体細胞の単一分子技法のような生物分子の物理学的特性研究、単一分子生物物理学とナノサイエンスとの統合などが討議されます。

1. Single-molecule fluorescence tracking/ 2. Single molecule studies in the membrane/ 3. Single-molecule imaging in live cells/ 4. Superresolution imaging/ 5. Fluorescence Resonance Energy Transfer/ 6. Single-molecule enzymology/ 7. Rotary proteins/ 8. Fluorescence Correlation Spectroscopy/ 9. Advanced Concepts of Fluorescence Fluctuation Spectroscopy/ 10. Nucleic-acid analysis at the single-molecule level/ 11. Nanopores: Geneneration and Single-Molecule Applications/ 12. Optical trapping/ 13. Magnetic tweezing/ 14. Protein/DNA unfolding/ 15. Single molecule recognition/ 16. Nano-scale AFM imaging/ 17. High Speed AFM/ 18. Recognition imaging/ 19. Atomic force microscopy of protein-protein interactions/ 20. A New Approach to Analysis of Single Molecule Force Measurements/ 21. Single Molecule Recognition: Extracting Information from Individual Binding Events and Their Correlation/ Index/ *

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He, B. B.
Two-dimensional X-ray Diffraction
２次元Ｘ線回折

John Wiley & Sons 2009.8
426 pp.(H)
ISBN 0-470-22722-2
　　　　　　　　　　　　　　　　　　　　　　　　　　　　13,400円

Contents
* Written by one of the pioneers of 2D X-Ray Diffraction, this useful guide covers the fundamentals, experimental methods and applications of two-dimensional x-ray diffraction, including geometry convention, x-ray source and optics, two-dimensional detectors, diffraction data interpretation, and configurations for various applications, such as phase identification, texture, stress, microstructure analysis, crystallinity, thin film analysis and combinatorial screening.

* Experimental examples in materials research, pharmaceuticals, and forensics are also given. This presents a key resource to researchers in materials science, chemistry, physics, and pharmaceuticals, as well as graduate-level students in these areas. *

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Leubner, I.
Precision Crystallization
Theory and Practice of Controlling Crystal Size

CRC Press 2009.9
216 pp.(H)
ISBN 1-4398-0674-8
　　　　　　　　　　　　　　　　　　　　　　　　　　　　23,300円

Contents
* Despite the fact that crystals make up an estimated 80% of chemical and pharmaceutical products, few resources exist that provide practical guidance on achieving precision control of their size and size distribution. Based on a model developed by the author and his colleagues, Precision Crystallization: Theory and Practice of Controlling Crystal Size presents scientists and product engineers with the tools to control crystal nucleation, enabling them to ultimately control crystal size and size distribution for batch and continuous crystallizations.

* At the cutting edge of crystallization science and technology, this volume presents information never before available. Introducing the Balanced Nucleation and Growth (BNG) model, the book demonstrates how the results of the nucleation process are quantitatively related to practical experimental control values such as: ・reaction addition rate ・crystal solubility ・temperature ・residence time (continuous crystallizations) ・the effect of ripening agents (crystal supersizing) during nucleation ・the effect of crystal growth restrainers (crystal nanosizing) during nucleation ・control of renucleation *

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Waigh, T.
Applied Biophysics
A Molecular Approach for Physical Scientists
応用生物物理学

John Wiley & Sons 2007.9
436 pp. (P)
ISBN 0-470-01718-X
　　　　　　　　　　　　　　　　　　　　　　　　　　　　8,100円

Contents
Preface / Acknowledgements / 1. The Building Blocks / 2. Mesoscopic Forces / 3. Phase Transitions / 4. Liquid Crystallinity / 5. Motility / 6. Aggregating Self-Assembly / 7. Surface Phenomena / 8. Biomacromolecules / 9. Charged Ions and Polymers / 10. Membranes / 11. Continuum Mechanics / 12. Biorheology / 13. Experimental Techniques / 14. Motors / 15. Structural Biomaterials / 16. Phase Behaviour of DNA / Appendix / Answers to Tutorial Questions / Index / *

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Walker, J. M. ed.
The Protein Protocols Handbook 3rd ed.
タンパク質プロトコールハンドブック　第３版

Humana Press 2009.11
1455 pp.(P)
ISBN 1-60327-474-X
　　　　　　　　　　　　　　　　　　　　　　　　　　　　14,800円

Contents
1.Quantitation of Proteins/ 2.Electrophoresis of Proteins and Peptides and Detection in Gels/ 3.Blotting and Detection Methods/ 4.Chemical Modification of Proteins and Peptide Production, Purification and Characterisation/ 5.Post-Translational Modifications/ 6.Antibody Techniques/ Index/

* Since the publication of the bestselling second edition of John Walker's widely acclaimed Protein Protocols Handbook, there have been continual methodological developments in the field of protein chemistry. This greatly enhanced third edition introduces 57 critically important new chapters, as well as significantly updating the previous edition's tried-and-true methods. Although the timely new chapters are spread throughout all of the book, the vital sectionﾊon post-translational modifications has been expanded most to reflect the increasing importance of these modifications inﾊthe understanding of protein function. *
86-36　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　登録日　10.01.26

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