Ulrich, G. H. ed.
RNA Editing
Springer-Verlag 2008.
232 pp.(H)
ISBN 3-540-73786-3
21,700円
Contents
1.Editing Reactions from the Perspective of RNA Structure/ 2.Editing of tRNA for Structure and Function/ 3.RNA Editing by Adenosine Deaminases that Act on RNA (ADARs)/ 4.Insertion/Deletion Editing in Physarum polycephalum/ 5.RNA Editing in Plant Mitochondria/ 6.RNA Editing in Chloroplasts/ 7.Working Together: the RNA Editing Machinery in Trypanosoma brucei / 8.RNA Editing Accessory Factors the Example of mHel61p / 9.The Function of RNA Editing in Trypanosomes/ 10.Evolutionary Aspects of RNA Editing/ Index/
* The term "RNA editing" describes a diverse set of biochemical processes whereby genetic information is modulated on a post-transcriptional level i.e. on the level of ribonucleic acids (RNA). RNA editing has been demonstrated in viruses, protozoan organisms, in plants and in mammals and in many cases it has been identified as a key step in the regulation of gene expression. *
Jeanteur, P. ed.
RNA Trafficking and Nuclear Structure Dynamics 2nd ed.
RNAの輸送と核構造のダイナミクス
Springer-Verlag 2008.
154 pp.(P)
ISBN 3-540-74265-4
10,700円
Contents
Part.1:Nuclear Organisation and Subnuclear Bodies: 1 Introduction / 2 Chromatin and Nuclear Compartments/ 3 The Nucleolus/ 4 Perinucleolar Compartment/ 5 Cajal Bodies, gems/ 6 Speckles- Nuclear Bodies Enriched in Splicing Factors/ 7 Promyelocytic Leukemia Bodies/ 8 Other Forms of Nuclear Bodies/ 9 Conclusion, Perspectives/ References/ Part.2:Searching for Active Ribosomal Genes: 1 Introduction/ 2 Historical Perspective/ 3 The Ups and Downs of Affinity Cytochemistry:the Case of the Nucleolus/ 4 Mapping of Active Ribosomal Genes/ 5 Conclusions/ References/ Part.3:Toxic RNA in the Nucleus: Unstable Microsatellite Expression in Neuromuscular Disease: 1 Overview/ 2 Unstable Microsatellites in Neurological and Neuromuscular Disease/ 3 RNA-Mediated Disease/ 4 Unstable Microsatellites, Toxic RNA and Implications for Nuclear Structure and Function/ References/ Part.4:Assembly and Traffic of Small Nuclear RNPs: 1 Introduction/ 2 Biogenesis of Small Nuclear RNPs/ 3 Biogenesis of Small Nucleolar RNPs (snoRNPs)/ 4 Noncanonical Types of Box C/D and Box H/ACA RNAs/ 5 Similarities Between snRNA and snoRNA Biogenesis/ 6 snRNAs and snoRNAs: a Common Origin?/ References/ Part.5:Intranuclear Pre-mRNA Trafficking in an Insect Model System: 1 The Balbiani Ring Genes of Chironomus tentans: a Model System for Studying Gene Expression in Situ/ 2 The Movement of the (pre)mRNP Particles from the Gene to the NPC/ 3 Conclusions/ References/ Part.6:Photobleaching Microscopy Reveals the Dynamics of mRNA-Binding Proteins Inside Live Cell Nuclei: 1 Introduction/ 2 General Concepts of Quantitative FRAP/ 3 FRAP Reveals the Dynamics of GFP-PABP2 and GFP-TAP in the Living Cell Nucleus/ 4 Estimating the Fraction of GFP Fusion Proteins Bound to mRNP Complexes by FLIP/ 5 Simulation of mRNP Mobility Within the Nucleus Using a Random Walk Model/ 6 Concluding Remarks/ References/ Part.7:Imaging of Single mRNAs in the Cytoplasm of Living Cells: 1 Rationale for Live Cell Imaging of mRNA/ 2 Existing Technologies for the Visualization of RNA in Living Cells/ 3 Analysis of Single RNA Dynamics in Living Cells/ 4 Time-Lapse Microscopy/Particle Tracking/ 5 In Vivo mRNA Analyses in the Cytoplasm/ 6 Conclusion/ References/ Subject Index/ *
Rossi, J. ed.
MicroRNA Methods
Methods in Enzymology Volume 427
Academic Press 2007.8
304 pp. (H)
ISBN 0-12-373917-9
20,100円
Contents
SECTION I. Identifying Micro RNAs and their targets Chapter 1: Identification of viral miRNAs Chapter 2: Robust machine learning algorithms predict microRNA genes and targets Chapter 3: Idenfication of virally encoded microRNAs Chapter 4: Computational Methods for microRNA Target Prediction SECTION II. Micro RNA expression, maturation and functional analysis Chapter 5: In vitro and in vivo assays for the activity of the Drosha-DGCR8 complex Chapter 6: Microarray analysis of microRNA gene expression. Chapter 7: Cloning and detecting signature microRNAs from mammalian cells Chapter 8: Approaches for studying microRNA and small interfering RNA methylation in vitro and in vivo Chapter 9: Analysis of small RNA profiles during development. Chapter 10: Dissecting MicroRNA-mediated Gene Regulation and Function in T Cell Development SECTION III. MiRNAs and Disease Chapter 11: Investigation of microRNAs alterations in leukemias and lymphomas Chapter 12: Discovery of pathogen-regulated small RNAs in plants Chapter 13: Protocols for expression and functional analysis of viral microRNAs *
Lilley, D. M. J. & Eckstein, F. ed.
Ribozymes and RNA Catalysis
Royal Society of Chemistry 2007.
318 pp.(H)
ISBN 0-85404-253-9
18,000円
Contents
* The discovery that RNA could act as a macromolecular catalyst in the cell, signified a paradigm shift in molecular biology. Ribozymes and RNA Catalysis takes the reader through the origins of catalysis in RNA and necessarily includes significant discussion of structure and folding. The main focus of the book concerns chemical mechanism with extensive comment on how, despite the importance of RNA catalysis in the cell, its origins are still poorly understood and often controversial.
* The reader is given an outline of the important role of RNA catalysis in many aspects of cell function, including RNA processing and translation. There has been a significant coming together in the field of RNA in recent years and this book offers a compelling review of the whole field to date.
* Written by leading experts in their field, who in turn review the structural and mechanistic data for all known ribozymes this book is well suited for undergraduates, postgraduates and researchers in catalytic chemistry as well as those in related fields who require a unique overview of the subject. *
Zempleni, J. et al.
Handbook of Vitamins 4th ed.
CRC Press 2007.6
608 pp. (H)
ISBN 0-8493-4022-5
21,100円
Contents
1. Vitamin A: Nutritional Aspects of Retinoids and Carotenoids / 2. Vitamin D / 3. Vitamin K / 4. Vitamin E / 5. Bioorganic Mechanisms Important to Coenzyme Functions / 6. Niacin / 7. Riboflavin (Vitamin B2) / 8. Thiamine / 9. Pantothenic Acid / 10. Vitamin B6 / 11. Biotin / 12. Folic Acid / 13. Vitamin B12 / 14. Choline / 15. Ascorbic Acid, C.S. Johnston / 16. Vitamin-Dependent Modifications of Chromatin: Epigenetic Events and Genomic Stability / 17. Accelerator Mass Spectrometry in the Study of Vitamins and Mineral Metabolism in Humans / 18. Dietary Reference Intakes for Vitamins / Index /
* Thoroughly revised and updated, Handbook of Vitamins highlights the most recent research in vitamins and gene expression, vitamin-dependent genes, and vitamin effect on DNA stability. This fourth edition includes new chapters on vitamin-dependent modification of chromatin, analysis of vitamin metabolism using accelerated mass spectrometry, and dietary reference intakes for vitamins. It encompasses classical and modern approaches to vitamins, focusing on human nutrition, vitamin analysis, and vitamin action at the molecular level. *
Howe, C.
Gene Cloning and Manipulation 2nd ed.
Cambridge University Press 2007.7
276 pp. (H)
ISBN 0-521-81793-5
15,800円
Contents
Preface; 1. The tools for the job; 2. Polymerase chain reaction; 3. Simple cloning; 4. Other vector systems for E. Coli; 5. Making libraries; 6. Screening libraries; 7. Modification and mutagenesis; 8. Use of cloned DNA; 9. Using other organisms; 10. Examples.
* Now fully updated to reflect recent advances, this introduction provides a broad, but concise, coverage of recombinant DNA techniques. Emphasis is placed on the concepts underlying particular types of cloning vectors to aid understanding and to enable readers to devise suitable strategies for novel experimental situations. A series of 'real-life' biological problems are also presented to enable readers to assess their understanding of the material and to prepare for exams. *
Lodge, J. et al.
Gene Cloning
principles and applications
Taylor & Francis 2006.9
356 pp. (P)
ISBN 0-7487-6534-4
9,200円
Contents
1. Introduction / 2. Genome Organisation / 3. Key Tools for Gene Cloning / 4. Gene Identification and DNA Libraries / 5. Screening DNA Libraries / 6. Further Routes to Gene Identification / 7. Sequencing DNA / 8. Bioinformatics / 9. Production of Proteins from Cloned Genes / 10. Gene Cloning in the Functional Analysis of Proteins / 11. The Analysis of the Regulation of Gene Expression / 12. The Production and Uses of Transgenic Organisms / 13. Forensic and Medical Applications. *
896-15 登録日 08.01.20
