Matthiesen, R. ed.
Mass Spectrometry Data Analysis in Proteomics
Methods in Molecular Biology Vol.367
Humana Press 2007.3
336 pp. (H)
ISBN 1-58829-563-X
16,600円
Contents
Preface. Contributors. 1 Introduction to Proteomics. 2 Extracting Monoisotopic Single-Charge Peaks From Liquid Chromatography-Electrospray Ionization-Mass Spectrometry. 3 Calibration of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Peptide Mass Fingerprinting Spectra. 4 Protein Identification by Peptide Mass Fingerprinting. 5 Generating Unigene Collections of Expressed Sequence Tag Sequences for Use in Mass Spectrometry Identification. 6 Protein Identification by Tandem Mass Spectrometry and Sequence Database Searching. 7 Virtual Expert Mass Spectrometrist v3.0: An Integrated Tool for Proteome Analysis. 8 Quantitation With Virtual Expert Mass Spectrometrist. 9 Sequence Handling by Sequence Analysis Toolbox v1.0. 10 Interpretation of Collision-Induced Fragmentation Tandem Mass Spectra of Posttranslationally Modified Peptides. 11 Retention Time Prediction and Protein Identification. 12 Quantitative Proteomics by Stable Isotope Labeling and Mass Spectrometry. 13 Quantitative Proteomics for Two-Dimensional Gels Using Difference Gel Electrophoresis. 14 Proteomic Data Exchange and Storage: Using Proteios. 15 Proteomic Data Exchange and Storage: The Need for Common Standards and Public Repositories. 16 Organization of Proteomics Data With YassDB. 17 Analysis of Carbohydrates by Mass Spectrometry. 18 Useful Mass Spectrometry Programs Freely Available on the Internet. Appendix. Index/ *
Sechi, S. ed.
Quantitative Proteomics by Mass Spectrometry
Methods in Molecular Biology Vol.359
Humana Press 2007.3
280 pp. (H)
ISBN 1-58829-571-0
13,900円
Contents
Preface. Contributors. 1 AcrylamideﾑA Cysteine Alkylating Reagent for Quantitative Proteomics. 2 Using Stable Isotope Tagging and Mass Spectrometry to Characterize Protein Complexes and to Detect Changes in Their Composition. 3 Stable Isotope Labeling by Amino Acids in Cell Culture for Quantitative Proteomics. 4 Quantitative Proteomics of Mouse Brain and Specific Protein-Interaction Studies Using Stable Isotope Labeling. 5 The Absolute Quantification Strategy: Application to Phosphorylation Profiling of Human Separase Serine 1126. 6 Quantification of Proteins and Metabolites by Mass Spectrometry Without Isotopic Labeling. 7 The Use of a Quantitative Cysteinyl-Peptide Enrichment Technology for High-Throughput Quantitative Proteomics. 8 An Isotope Coding Strategy for Proteomics Involving Both Amine and Carboxyl Group Labeling. 9 Proteolytic Labeling With 18O for Comparative Proteomics Studies: Preparation of 18O-Labeled Peptides and the 18O/16O Peptide Mixture. 10 Tandem Mass Spectrometry in the Detection of Inborn Errors of Metabolism for Newborn Screening. 11 Absolute Quantification of Specific Proteins in Complex Mixtures Using Visible Isotope-Coded Affinity Tags. 12 Computational Analysis of Quantitative Proteomics Data Using Stable Isotope Labeling. 13 Quantitative Proteomic Analysis of Mammalian Organisms Using Metabolically Labeled Tissues. 14 Quantitative Proteomic Analysis of Phosphotyrosine-Mediated Cellular Signaling Networks. Index/ *
Kazakevich, Y. V. & LoBrutto, R.
HPLC for Pharmaceutical Scientists
John Wiley & Sons 2007.1
1104 pp. (H)
ISBN 0-471-68162-8
21,600円
Contents
PREFACE / CONTRIBUTORS / PART I HPLC THEORY AND PRACTICE. 1 Introduction / 2 HPLC Theory / 3 Stationary Phases / 4 Reversed-Phase HPLC / 5 Normal-Phase HPLC / 6 Size-Exclusion Chromatography / 7 LC/MS: Theory, Instrumentation, and Applications to Small Molecules / 8 Method Development / 9 Method Validation / 10 Computer-Assisted HPLC and Knowledge Management / PART II HPLC IN THE PHARMACEUTICAL INDUSTRY. 11 The Expanding Role of HPLC in Drug Discovery / 12 Role of HPLC in Preformulation / 13 The Role of Liquid Chromatography�廴ass Spectrometry in Pharmacokinetics and Drug Metabolism / 14 Role of HPLC in Process Development / 15 Role of HPLC During Formulation Development / 16 The Role of HPLC in Technical Transfer and Manufacturing PART III HYPHENATED TECHNIQUES AND SPECIALIZED HPLC SEPARATIONS. 17 Development of Fast HPLC Methods / 18 Temperature as a Variable in Pharmaceutical Applications / 19 LC/MS Analysis of Proteins and Peptides in Drug Discovery / 20 LC-NMR Overview and Pharmaceutical Applications / 21 Trends in Preparative HPLC / 22 Chiral Separations / CHEMICAL AND DRUG COMPOUND INDEX / SUBJECT INDEX /
* This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development.
* The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed. *
Schalley, C. ed.
Analytical Methods in Supramolecular Chemistry
超分子化学の分析手法
Wiley -VCH 2007.3
502 pp. (H)
ISBN 3-527-31505-5
23,600円
Contents
Preface. / List of Contributors. / 1. Introduction. / 2. Determination of Binding Constants. / 3. Isothermal Titration Calorimetry in Supramolecular Chemistry. / 4. Extraction Methods. / 5. Mass Spectrometry and Gas Phase Chemistry of Supramolecules. / 6. Diffusion NMR in Supramolecular Chemistry. / 7. Photophysics and Photochemistry of Supramolecular Systems. / 8. Circular Dichroism Spectroscopy. / 9. Crystallography and Crystal Engineering. / 10. Scanning Probe Microscopy. / 11. The Characterization of Synthetic Ion Channels and Pores. / 12. Theoretical Methods for Supramolecular Chemistry. / Index. **
* An overview of the techniques used to examine supramolecular aggregates from a methodological point of view. Edited by a rising star in the community and an experienced author, this is a definitive survey of useful modern analytical methods for understanding supramolecular chemistry, from NMR to single-molecule spectroscopy, from electron microscopy to extraction methods. A definitive study of this field touching many interdisciplinary areas such as molecular devices, biology, bioorganic chemistry, material science, and nanotechnology. *
Rosner, P. et al.
Mass Spectra of Designer Drugs
Including Precursors, Medicinal Drugs and Chemical Warfare Agents
（薬物解析データ）
Wiley -VCH 2007.3
2087 pp. (H)
ISBN 3-527-30798-2
104,000円
Contents
* The collection contains 8800 records obtained from 4379 compounds from the following categories: - designer drugs - medicinal drugs - chemical warfare agents - explosives
* Each record contains the following data: - full or expanded mass spectrum (150 peaks on average) - IUPAC name, WHO name (if any) - synonyms and proprietary names - legal category information according to United Nations, U.S.A. and German standards - information on therapeutic and illicit modes of use - structural formula - molecular formula and exact molecular weight - CAS number - GC retention index (measured or calculated) - information on recording conditions - spectrum quality index (according to McLafferty) and verification index (matching with spectra from other published collections)
* Based on the authors' several decades of professional experience, this unique data collection is tailor-made for criminal and forensic investigators. It contains 8,800 mass spectrum records obtained from 4,379 compounds categorized as either designer or medicinal drugs, chemical warfare agents or explosives. It even covers those substances yet to be recorded by the police, but which are likely to be encountered by crime prevention and investigation authorities, in both the areas of illicit drugs and homeland security. The perfect companion for users of the Roesner database, this print edition features a wealth of additional data not contained in the online version, such as U.S. and U. N. legal category information, chromatographic data and mass spectrum quality and similarity indices. *
991-8 登録日 07.05.31
